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Recombinant Mouse Tumor-associated calcium signal transducer 2 (Tacstd2), partial

Recombinant Mouse Tumor-associated calcium signal transducer 2 (Tacstd2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Tacstd2

Purity

>85% (SDS-PAGE)

Target Names

Tacstd2

Uniprot NO.

Q8BGV3

Alternative Names

Tacstd2; Trop2; Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

May function as a growth factor receptor.

Gene References into Functions

studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins. PMID:25523132
Trop2 is a regulator of self-renewal, proliferation, and transformation PMID:23070813
TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development. PMID:22194864
these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas. PMID:21970857
In human and mouse, Trop2 is highly expressed at both the transcript and protein levels on several essential normal tissues. PMID:21551320
Study also provides the first indication of a molecular signaling pathway activated by Trop2 which has important implications for cancer cell growth and survival. PMID:20858281
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics. PMID:19088204