Recombinant Mouse Trophoblast glycoprotein (Tpbg), partial

Code: CSB-MP7221MO
Size:
20ug
20ug100ug1mg
US$138
Quantity:
Express system: Mammalian cell
Species: Mus musculus (Mouse)
Tag Info: C-terminal 10xHis-tagged
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Product Details

Abbreviation
Recombinant Mouse Tpbg protein, partial
Purity
Greater than 95% as determined by SDS-PAGE.
Target Names
Tpbg
Uniprot NO.
Research Area
Cancer
Species
Mus musculus (Mouse)
Source
Mammalian cell
Expression Region
32-361aa
Mol. Weight
37.1 kDa
Protein Length
Partial
Tag Info
C-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Troubleshooting and FAQs
Datasheet & COA
Please contact us to get it.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Gene References into Functions
  1. The surface expression of 5T4 marks the use of the CXCR4 rather than the CXCR7 receptor, with distinct consequences for CXCL12 exposure. PMID:22956548
  2. 5T4 overexpression in newborn olfactory bulb interneurons facilitates their dendritic arborization even under a sensory input-deprived condition. PMID:22323733
  3. molecular interaction of 5T4 and CXCR4 occurring at the cell surface which directly facilitates the biological response to CXCL12 PMID:20376365
  4. Spry4 and Tpbg/5T4 were detected in Kit-immunoreactive cells only in Kit(K641E), but not in Kit(WT/WT) animals. PMID:19453770
  5. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen PMID:11903056
  6. 5T4 glycoprotein expression is associated with early differentiative events of embryonic stem cells PMID:14576347
  7. A limited expression profile of 5T4 may contribute to the migration of actively cycling, undifferentiated epithelial progenitor cells during embryogenesis PMID:15977177
  8. Because 5T4 is known to interact with actin cytoskeleton, these observations suggest that 5T4 is involved in the formation or maintenance of strata-specific dendritic ramification or synaptic connection of subsets of local interneurons. PMID:16506198
  9. E-cadherin protein stabilizes cortical actin cytoskeletal arrangement in embryonic stem cells, and this can prevent cell surface localization of the promigratory 5T4 antigen. PMID:17507657

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Highly expressed in embryo and placenta. In adult, expressed only in brain and ovary. Not detected in kidney small intestine, heart, spleen, testis, liver, lung, thymus and stomach.
Database Links
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No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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