Recombinant Mouse Transcription factor jun-D (Jund)

1. Differentiation-mediated activation of JunD results in enhanced TUBB4a expression in P19 embryonal carcinoma cells. PMID:25649943
2. JunD provides protection in aging-induced endothelial dysfunction and may represent a novel target to prevent reactive oxygen species-driven vascular aging. PMID:23410942
3. Nfe2 modulates JunD binding to the Gcm1 promoter via acetylation PMID:22174410
4. 5-HT2B blockade enhances liver regeneration by inhibiting induction of TGF-beta1 expression by hepatic stellate cells that is dependent on 5-HT, ERK and JunD. PMID:22120177
5. Downregulation of JunD and cyclin D1 expression in myofibroblasts may be important regarding the mechanism of action of MTA in Mdr2-/- mice PMID:21209952
6. Study supports potential roles for jun D, jun B, and fra-1 in the dietary energy restriction regulation of AP-1 function in the Sencar mouse skin carcinogenesis model. PMID:20232358
7. protects cells from p53-dependent senescence and apoptosis PMID:11106750
8. Translation initiation from alternative AUG and non-AUG sites in human, mouse and rat. PMID:12105216
9. Transcriptional activation of Ifi202 gene by Rb/JunD may be important for the regulation of cell growth and survival. PMID:12894219
10. Data suggest that JunD is part of a regulatory network that controls proliferation to prevent pathological progression in chronic renal diseases. PMID:12975469
11. regulatory role of JunD in T lymphocyte proliferation and Th cell differentiation PMID:15029240
12. menin suppresses osteoblast maturation, in part, by inhibiting the differentiation actions of JunD PMID:15563473
13. junD promotes both adaptive-protective and maladaptive hypertrophy in heart, depending on its expression levels. PMID:15655111
14. JunD limits cardiomyocyte hypertrophy and protects the pressure-overloaded heart from cardiac apoptosis PMID:16129800
15. stimulation of splenic B cells with IL-4 or IL-21 induced high Bcl6 expression with induction of junD PMID:16702165
16. In conclusion, a signaling pathway for the development of fibrosis involves the regulation of TIMP-1 expression by phosphorylated JunD. PMID:17133482
17. These data identify junD proto-oncogene (JunD) and Fos-related antigen 2 (Fra-2) as the activator protein-1 (AP-1) factors responsible for the RANKL-induced upregulation of the mouse Tcirg1 gene expression. PMID:17419679
18. both UV and H(2)O(2 )induce the activation of c-Fos/JunD AP-1 complexes resulting in the prevention of cell death PMID:17531086
19. JunD counterbalances JNK1 activation and the downstream redox-dependent hepatic injury that results from I/R, and may do so by regulating NADPH oxidases PMID:18182393
20. JunD is involved in estrogen depletion-induced osteopenia via its action to suppress bone formation and to enhance bone resorption. PMID:18240141
21. JunD-menin complex plays significant roles in the androgen-dependent differentiation of the duct system in the mouse submandibular gland PMID:18323693

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UNIGENE: Mm.419851

KEGG: mmu:16478

STRING: 10090.ENSMUSP00000092901