Recombinant Mouse Tartrate-resistant acid phosphatase type 5 (Acp5)

1. TRAP and nidogen-2 co-localized in adipose tissue cells in situ. PMID:25450682
2. Uteroferrin is a cytokine secreted by uterine glands in response to progesterone that promotes fetal erythropoiesis at various stages of pregnancy. PMID:25093463
3. Supraphysiologic oscillatory fluid shear induces upregulation of osteoclastic activity, measured by tartrate-resistant acid phosphatase activity and formation of mineral resorption pits. PMID:24275439
4. Pax6 binds endogenously to the proximal region of the tartrate acid phosphatase (TRAP) gene promoter and suppresses nuclear factor of activated T cells c1 (NFATc1)-induced TRAP gene expression. PMID:23990468
5. Serum TRAP levels were lower in mice receiving eggshell calcium citrate malate than those receiving eggshells calcium malate. PMID:23603074
6. tartrate resistant acid phosphatase PMID:23444125
7. TRAP is not essential for the formation of the epiphyseal vascular network. PMID:22579636
8. dephosphorylation of Man6P-containing lysosomal proteins requires the concerted action of Acp2 and Acp5 and is needed for hydrolysis and removal of degradation products PMID:22158965
9. Accumulation of vesicles in the cytoplasm of mutant osteoclasts indicates a novel function for tartrate-resistant acid phosphatase in modulating intracellular vesicular transport in osteoclasts PMID:12243748
10. USF1 and USF2 play a functional role in RANKL-dependent TRAP expression during osteoclast differentiation. PMID:12663664
11. TRACP expression is a target for regulation by the macrophage/osteoclast transcription factor PU.1 and the osteoclast commitment factor MiTF PMID:14584903
12. YY1 plays a functional role in RANKL-mediated TRAP gene expression during osteoclast differentiation. PMID:15563837
13. distinct tartrate-resistant acid phosphatase promoter regions have distinct roles in gene regulation in transgenic mice PMID:15590658
14. MMP-2 and MMP-9 expression by TRAP positive mononuclear and multinucleated cells are involved in articular cartilage destruction in CIA. PMID:15862156
15. TRAP release is due to secretion, rather than cell death PMID:16475168
16. TRACP is important for polarizing responses in naive T cells to antigen-presented dendritic cells. PMID:16939395
17. both synthesis as well as degradation of collagen are increased when TRAP is absent in mice at 8 weeks and 6 months of age, showing that TRAP has an important role in the metabolism of collagen PMID:17551769
18. transcriptional activity of the Tracp gene, in pre-osteoclastic cells, is negatively regulated by the binding of PARP-1 protein to a potential consensus sequence located in its promoter region PMID:18021007
19. prolonged hypoxia induces the formation of TRAP-positive osteoclast-like cells, suggesting the occurrence of an autocrine mechanism for osteoclastogenesis PMID:18056037
20. Over-expression of monomeric tartrate resistant acid phosphatase, but not the dimeric form in adipose tissue leads to early onset spontaneous hyperplastic obesity PMID:18320034
21. central role for ACP5 in removal of the Man-6-P recognition marker from lysosomal proteins, which are then dephosphorylated PMID:18940929
22. in the absence of RANKL and osteoclast differentiation, STAT6 binds the TRAP promoter after IL-4 treatment and directly enhances TRAP expression PMID:19801646

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UNIGENE: Mm.46354

KEGG: mmu:11433

STRING: 10090.ENSMUSP00000065425