Home
Product
Protein
Recombinant Proteins
Recombinant Mouse Serine/threonine-protein kinase D3 (Prkd3), partial

Recombinant Mouse Serine/threonine-protein kinase D3 (Prkd3), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

Prkd3

Purity

>85% (SDS-PAGE)

Target Names

Prkd3

Uniprot NO.

Q8K1Y2

Alternative Names

Prkd3; PrkcnSerine/threonine-protein kinase D3; EC 2.7.11.13; Protein kinase C nu type; nPKC-nu

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

1-889

Target Protein Sequence

MSANNSPPSA QKSVFPATVS AVLPAPSPCS SPKTGLSARL SNGSFSAPSL TNSRGSVHTV SFLLQIGLTR ESVTIEAQEL SLSAVKDLVC SIVYQKFPEC GFFGMYDKIL LFRHDMNSEN ILQLITSADE IHEGDLVEVV LSALATVEDF QIRPHALYVH SYKAPTFCDY CGEMLWGLVR QGLKCEGCGL NYHKRCAFKI PNNCSGVRKR RLSNVSLPGP GLSVPRPLQP ECVPLLSEES HTHQEPSKRI PSWSGRPIWM EKMVMCRVKV PHTFAVHSYG RPTICQYCKR LLKGLFRQGM QCKDCKFNCH KRCASKVPRD CLGEVTFNGE PCSVGTDADM PMDIDSSDVN SDGSRGLDDS EEPSPPEDKM FFLDPTDLDV ERDEETVKTI SPSTSNNIPL MRVVQSIKHT KRRSSTVVKE GWMVHYTSRD NLRKRHYWRL DSKCLTLFQN ESGSKYYKEI PLSEILRVSS PQDFTSISQG SNPHCFEIIT DTVVYFVGEN NGSSSHNPVL AATGVGLDVA QSWEKAIRQA LMPVTPQASV CTSPGQGKDH NLATSISVSN CQVQENVDIS SVYQIFADEV LGSGQFGIVY GGKHRKTGRD VAIKVIDKMR FPTKQESQLR NEVAILQNLH HPGIVNLECM FETPERVFVV MEKLHGDMLE MILSSEKSRL PERITKFMVT QILVALRNLH FKNIVHCDLK PENVLLASAE PFPQVKLCDF GFARIIGEKS FRRSVVGTPA YLAPEVLRSK GYNRSLDMWS VGVIVYVSLS GTFPFNEDED INDQIQNAAF MYPPNPWREI SSEAIDLINN LLQVKMRKRY SVDKSLSHPW LQDYQTWLDL REFETRIGER YITHESDDAR WEIHAYTHNL EYPKHFIMAP NPDDMEEDP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.

Gene References into Functions

These data provide new insights of a specific PKD3 signaling pathway by identifying a new function, which has not been identified before. PMID:27245420
Erythropoietin regulates GATA1 through protein kinase D activation, promoting histone deacetylase 5 dissociation from GATA1, and subsequent GATA1 acetylation. PMID:22983445
These data validate PKD3 as a promising therapeutic target in prostate cancer and shed light on the role of secreted tumor-promoting factors in prostate cancer progression. PMID:22532599
PKCnu is an important component of signaling pathways downstream from novel PKC enzymes after B-cell receptor engagement PMID:12506120
the catalytic activity of PKD3 may regulate its nuclear import through autophosphorylation and/or interaction with another protein PMID:16380377
PKD3 is increasingly expressed in neuronal as well as in the supporting connective tissue and in skeletal muscles PMID:18439271
reveal a novel distinction between the exocrine and endocrine cells of the pancreas and further identify PKD3 as a signaling molecule that promotes hormone-stimulated amylase secretion PMID:19028687