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Recombinant Mouse Selenium-binding protein 1 (Selenbp1)

Recombinant Mouse Selenium-binding protein 1 (Selenbp1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Selenbp1

Uniprot NO.

P17563

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

2-472

Target Protein Sequence

ATKCTKCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYSQVI HRLPMPYLKD ELHHSGWNTC SSCFGDSTKS RNKLILPGLI SSRIYVVDVG SEPRAPKLHK VIEASEIQAK CNVSSLHTSH CLASGEVMVS TLGDLQGNGK GSFVLLDGET FEVKGTWEKP GDAAPMGYDF WYQPRHNVMV STEWAAPNVF KDGFNPAHVE AGLYGSRIFV WDWQRHEIIQ TLQMTDGLIP LEIRFLHDPS ATQGFVGCAL SSNIQRFYKN AEGTWSVEKV IQVPSKKVKG WMLPEMPGLI TDILLSLDDR FLYFSNWLHG DIRQYDISNP QKPRLAGQIF LGGSIVRGGS VQVLEDQELT CQPEPLVVKG KRIPGGPQMI QLSLDGKRLY ATTSLYSAWD KQFYPDLIRE GSMMLQIDVD TVNGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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■ Customer Reviews

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Target Background

Function(From Uniprot)

Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.

Gene References into Functions

These results have revealed a novel mechanism that SELENBP1-mediated cancer inhibition is through altering lipid/glucose metabolic signaling pathways. PMID:25974208
Selenbp1 suppresses the expression of tumor-promoting genes PMID:23500078
SBP1 has tumor suppressor functions that are inhibited in colorectal cancer through epigenetic silencing PMID:19924303

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Subcellular Location

Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein.

Protein Families

Selenium-binding protein family

Tissue Specificity

Highly expressed in liver, kidney and, to a lesser extent, lung.

Database Links

UNIGENE: Mm.196558

KEGG: mmu:20341

STRING: 10090.ENSMUSP00000088349

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