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Recombinant Mouse Secretoglobin family 3A member 1 (Scgb3a1)

Recombinant Mouse Secretoglobin family 3A member 1 (Scgb3a1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Scgb3a1

Purity

>85% (SDS-PAGE)

Target Names

Scgb3a1

Uniprot NO.

Q920D7

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

22-104

Target Protein Sequence

FFMDSLAKP AVEPVAALAP AAEAVAGAVP SLPLSHLAIL RFILASMGIP LDPLIEGSRK CVTELGPEAV GAVKSLLGVL TMFG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Secreted cytokine-like protein. Inhibits cell growth in vitro.

Gene References into Functions

Neonatal hyperoxia followed by RA recovery was associated with decreased lung CCSP and SCGB3A1 protein but not mRNA expression. PMID:24187664
The differential expression of mRNA by both airway level and lung region was determined for uteroglobin-related protein 2. PMID:20852037
Highest HIN-1 and UGRP-1 expression is detected in the lung, while lower level HIN-1 expression is also detected in the stomach, heart, small intestine, uterine and mammary glands PMID:12175512
genomic structure and expression patterns of Ugrp2 and its alternative spliced form were characterized PMID:12438750
EGF-induced increase of Ugrp2 occurred at the transcriptional level that required the EGF receptor and the activation of the ERK-MAPK and phosphoinositide-3 kinase pathways PMID:15811345
ubiquitous transcription factor NF-Y binds to and activates expression of the Scgb3a1 gene and tissue-specific expression of the gene is associated with CpG methylation of the promoter PMID:18194566
The expression of SCGB3A1 and SCGB3A2 are bidirectionally regulated by oncostatin M (OSM) when examined in a mouse transformed Clara cell line. PMID:18978304
Expression of SCGB3A1 was down-regulated by IFN-gamma in a time- and dose-dependent manner in the murine transformed Clara Cells line. PMID:19135978

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Subcellular Location

Secreted.

Protein Families

Secretoglobin family, UGRP subfamily

Tissue Specificity

Highly expressed in lung, where it localizes to epithelial cells lining the trachea and bronchi. Expression in lung is mainly restricted to bronchi, submucosal glands of the trachea, and tracheal epithelium, with little expression in terminal bronchioles.

Database Links

UNIGENE: Mm.22802

KEGG: mmu:68662

STRING: 10090.ENSMUSP00000043325

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