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Recombinant Mouse Retinoic acid early-inducible protein 1-epsilon (Raet1e)

Recombinant Mouse Retinoic acid early-inducible protein 1-epsilon (Raet1e)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Raet1e

Purity

>85% (SDS-PAGE)

Target Names

Raet1e

Uniprot NO.

Q9CZQ6

Alternative Names

Raet1e; Retinoic acid early-inducible protein 1-epsilon; RAE-1-epsilon

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

29-227

Target Protein Sequence

LD DAHSLRCNLT IKDPTSADLP WCDVKCSVDE ITILHLNNIN KTMTSGDPGK MANATGKCLT QPLNDLCQEL RDKVSNTKVD THKTNGYPHL QVTMIYPQSQ GQTPSATWEF NISDSYFFTF YTENMSWRSA NDESGVIMNK WKDDGDLVQQ LKYFIPQCRQ KIDEFLKQSK EKPRSTSRSP SITQLTSTSP LPPPSHS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Acts as a ligand for KLRK1.

Gene References into Functions

Study reports that retinoic acid early induced transcript-1-d and retinoic acid early induced transcript-1-e (Raet1) genes are induced early upon experimental autoimmune encephalomyelitis onset and reach a maximal expression at the peak of the pathology. Study also shows that macrophages as well as microglia, are cellular sources of Raet1 transcripts. PMID:27444966
CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1epsilon transgenic mice. PMID:24708417
Reveal Raet1e, a major histocompatibility complex class 1-like molecule expressed in lesional aortic endothelial cells and macrophage-rich regions, as a novel atherosclerosis gene. PMID:23948654
Raet1e genes are directly transcriptionally activated by E2F family transcription factors, which play a central role in regulating cell cycle entry. PMID:23166357
RAE1 expression was sufficient to induce the recruitment of adoptively transferred CTLs to islets. PMID:22244846