Recombinant Mouse Protein boule-like (Boll)

Product Details

Abbreviation
Boll
Purity
>85% (SDS-PAGE)
Target Names
Boll
Uniprot NO.
Species
Mus musculus (Mouse)
Source
Yeast
Expression Region
1-281
Target Protein Sequence
MQTDSLSPSP NPVSPVPLNN PTSGPRYGTV IPNRIFVGGI DFKTNENDLR KFFSQYGSVK EVKIVNDRAG VSKGYGFITF ETQEDAQKIL QEAEKLNYKD KKLNIGPAIR KQQVGIPRSS LMPAAGTMYL TTSTGYPYTY HNGVAYFHTP EVTSVPPSWP SRSISSSPVM VAQPVYQQPA YHYQAPAQCL PGQWQWGVPQ SPASSAPFLY LQPSEVIYQP VEIAQDGGCV PPPLSLMETS VPEPYSDHGV QAAYHQVYAS SAIAMPAPMM QPEPIKVRSL F
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
Gene References into Functions
  1. asked whether BOULE, the founding member of DAZ family proteins, is a component of the SGs. We show that BOULE is recruited to the SGs upon heat stress, and that these SGs are developmental stage-specific PMID:27632217
  2. These results showed that IGF1 regulated the expression of BOULE and CDC25A mRNAs via ERK1/2 signaling and in T-independent pathway during spermatogenesis in the adult mouse testes. PMID:25726377
  3. demonstrate that Boll is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl PMID:24086306
  4. Expression of key regulators of spermiogenesis was unaffected in Boule(-/-) mice, suggesting that Boule regulates germ-cell differentiation through a novel pathway. PMID:20335278

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Subcellular Location
Cytoplasm.
Protein Families
RRM DAZ family
Tissue Specificity
Testis specific. Not expressed in early embryos, primoridal germ cells and spermatogonial cells. First expressed in the cytoplasm of spermatocytes and then persists through meiosis.
Database Links
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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