Recombinant Mouse Protein FAM46C (Fam46c)

Product Details

Abbreviation
Fam46c
Purity
>85% (SDS-PAGE)
Target Names
Fam46c
Uniprot NO.
Alternative Names
Tent5c; Fam46c; Terminal nucleotidyltransferase 5C; EC 2.7.7.19
Species
Mus musculus (Mouse)
Source
Yeast
Expression Region
1-391
Target Protein Sequence
MAEEGSSTKD SESFSVLNWD QVSRLHEVLT EVVPIHGRGN FPTLEITLKD IVQTVRGRLE EAGINVQDVR LNGSAAGHVL VKDNGLGCKD LDLIFHVALP TEAEFQLVRD VVLCSLLNFL PEGVNKLKIS PVTLKEAYVQ KLVKVCTDTD RWSLISLSNK NGRNVELKFV DSIRRQFEFS VDSFQIILDS LLFFYDCSGN PISEHFHPTV IGESMYGDFE EAFDHLQNRL IATKNPEEIR GGGLLKYSNL LVRDFRPADQ EEIKTLERYM CSRFFIDFPD ILEQQRKLET YLQNHFSDEE RSKYDYLMIL RRVVNESTVC LMGHERRQTL NLISLLALRV LAEQNIIPSA TNVTCYYQPA PYVSDGNFNN YYIAHPPITY SQPYPTWLPC N
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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 Customer Reviews

Target Background

Function(From Uniprot)
Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase which enhances mRNA stability and gene expression. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein and may be involved in induction of cell death.
Gene References into Functions
  1. FAM46C protein is strongly induced during activation of primary splenocytes and that B lymphocytes isolated from newly generated FAM46C KO mice proliferate faster than those isolated from their WT littermates. PMID:28931820

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
FAM46 family
Tissue Specificity
Expressed by splenocytes, expression is increased in activated splenocytes.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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