Recombinant Mouse P2X purinoceptor 6 (P2rx6), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
P2rx6
Uniprot NO.
Alternative Names
P2rx6; P2rxl1; P2X purinoceptor 6; P2X6; ATP receptor; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1
Species
Mus musculus (Mouse)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Receptor for ATP that acts as a ligand-gated ion channel.
Gene References into Functions
  1. purinergic signaling via P2X6 is not significantly involved in the regulation of renal electrolyte handling under normal physiological conditions. PMID:27254077
  2. once inside the nucleus, P2X6 subunit interacts with the splicing factor 3A1, which ultimately results in a reduction of the mRNA splicing activity PMID:25874565
  3. Immunoreactivity for P2X3-, P2X5-, and P2X6-purinoceptors was observed in mouse retina. PMID:17605080
  4. This study provides the first evidence that P2X8 receptors are expressed on LHRH-containing neurons. PMID:19442872

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
P2X receptor family
Tissue Specificity
Predominantly expressed in skeletal muscle. Also expressed in lung.
Database Links

UNIGENE: Mm.8032

KEGG: mmu:18440

STRING: 10090.ENSMUSP00000023441

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