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Recombinant Mouse Oligodendrocyte-myelin glycoprotein (Omg)

Recombinant Mouse Oligodendrocyte-myelin glycoprotein (Omg)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Omg

Purity

>85% (SDS-PAGE)

Target Names

Omg

Uniprot NO.

Q63912

Alternative Names

Omg; OmgpOligodendrocyte-myelin glycoprotein

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

25-417

Target Protein Sequence

ICPLQC TCTERHRHVD CSGRNLTTLP PGLQENIIHL NLSYNHFTDL HNQLTPYTNL RTLDISNNRL ESLPAQLPRS LWNMSAANNN IKLLDKSDTA YQWNLKYLDV SKNMLEKVVL IKNTLRSLEV LNLSSNKLWT VPTNMPSKLH IVDLSNNSLT QILPGTLINL TNLTHLYLHN NKFTFIPEQS FDQLLQLQEI TLHNNRWSCD HKQNITYLLK WVMETKAHVI GTPCSKQVSS LKEQSMYPTP PGFTSSLFTM SEMQTVDTIN SLSMVTQPKV TKTPKQYRGK ETTFGVTLSK DTTFSSTDRA VVAYPEDTPT EMTNSHEAAA ATLTIHLQDG MSSNASLTSA TKSPPSPVTL SIARGMPNNF SEMPRQSTTL NLRREETTAN GNTRPPS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.

Gene References into Functions

study provided in vitro and in vivo evidence that endogenous OMgp plays an important role in oligodendrocyte differentiation and myelination PMID:21352918
While myelin-derived axon growth inhibitor OMG may modulate axon sprouting, it does not play a major role in central nervous system axon regeneration failure. PMID:20547125
This allelic series will aid in the study of OMgp in adult CNS axon regeneration using mouse models of spinal cord injury. PMID:19672953
Expression of Omg protein in the embryonic mouse telencephalon indicates Omg has a role in axonal target specification and synaptic plasticity. PMID:19892785
Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. PMID:12068310