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Recombinant Mouse Nuclear factor of activated T-cells, cytoplasmic 3 (Nfatc3), partial

Recombinant Mouse Nuclear factor of activated T-cells, cytoplasmic 3 (Nfatc3), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Nfatc3

Uniprot NO.

P97305

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

2-1075

Target Protein Sequence

TTANCGAHD ELDFKLVFGE DGAPAPPPPG SRPADLEPDD CASIYIFNVD PPPSTLTTPL CLPHHGLPSH SSVLSPSFQL QSHKNYEGTC EIPESKYSPL GGPKPFECPS IQFTSISPNC QQELDAHEDD LQINDPEREF LERPSRDHLY LPLEPSYRES SLSPSPASSI SSRSWFSDAS SCESLSHIYD DVDSELNEAA ARFTLGSPLT SPGGSPGGCP GEESWHQQYG SGHSLSPRQS PCHSPRSSIT DENWLSPRPA SGPSSRPTSP CGKRRHSSAE VCYAGSLSPH HSPVPSPGHS PRGSVTEDTW LTAPVHTGSG LSPAPFPFQY CVETDIPLKT RKTSEDQAAI LPGKLEICSD DQGNLSPSRE TSVDDGLGSQ YPLKKDSSGD QFLSVPSPFT WSKPKPGHTP IFRTSSLPPL DWPLPTHFGQ CELKIEVQPK THHRAHYETE GSRGAVKAST GGHPVVKLLG YSEKPINLQM FIGTADDRYL RPHAFYQVHR ITGKTVATAS QEIIIASTKV LEIPLLPENN MSASIDCAGI LKLRNSDIEL RKGETDIGRK NTRVRLVFRV HIPQPSGKVL SLQIASIPVE CSQRSAQELP HIEKYSINSC SVNGGHEMIV TGSNFLPESK IIFLEKGQDG GPHWEVEGKI IREKCQGAHI VLEVPPYHNP AVTSAVQVHF YLCNGKRKKS QSQRFTYTPV LMKQEQREDT DLPSVPSLPV PHSAQAQRPS SETGHPHDRA MSAPGGLLCQ VQPAYTSMVA STHLPQLQCR DEGAGKEQHI ATSSVMHQPF QVTPTSPIGS SYQSIQTSMY NGPTCLPVNP ASSQEFDPVL FQQDAALSSL VNLGCQPLSP IPFHSSNSDA TGHLLAHSPH SVQTPPHLQS MGYHCSNAGQ TALSSPVADQ ITGQPSSHLQ PITYCPSHPG SATAASPAAS HPLASSPISG PSSPQLQPMP YQSPSSGTAS SPSPTTRMHS GQHSTQAQST GQGGLSVPSS LVCHSLCDPA SFPPGGATVS IKPEPEDQEP NFATIGLQDI TLDDVNEIIG RDMSQISVSQ ATEVMRDTPL PGPASPDLMT SHSAH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2. Along with NFATC4, involved in embryonic heart development.

Subcellular Location

Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.

Tissue Specificity

Expressed in thymus. Weakly expressed in muscle, spleen and kidney. Also expressed in lymph node. Expressed in the heart.

Database Links

UNIGENE: Mm.383185

STRING: 10090.ENSMUSP00000104931

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