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Recombinant Mouse Myeloid cell surface antigen CD33 (Cd33), partial

Recombinant Mouse Myeloid cell surface antigen CD33 (Cd33), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Cd33

Purity

>85% (SDS-PAGE)

Target Names

Cd33

Uniprot NO.

Q63994

Alternative Names

Cd33; Siglec3Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; Siglec-3; CD antigen CD33

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially binds sialic acid to the short O-linked glycans of certain mucins.

Gene References into Functions

Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs. PMID:25320078
CD33-related Siglec-E recognizes the intact neuron and has neuroprotective function by preventing phagocytosis. PMID:24227736
mCD33 is expressed on myeloid precursors in the bone marrow PMID:12773563
SOCS3 inhibited the CD33-induced block on cytokine-induced proliferation. SOCS3 and its target protein CD33 are degraded concomitantly concomitantly. PMID:17008544