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Recombinant Mouse MAX gene-associated protein (Mga), partial

Recombinant Mouse MAX gene-associated protein (Mga), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Mga

Uniprot NO.

A2AWL7

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

1-3003

Target Protein Sequence

MEEKQQIILA NQDGGTVTGG APTFFVILKQ PGNGKTDQGI LVTNRDARAL LSRESSPGKS KEKICLPADC TVGKITVTLD NNSMWNEFHN RSTEMILTKQ GRRMFPYCRY WITGLDSNLK YILVMDISPV DSHRYKWNGR WWEPSGKAEP HILGRVFIHP ESPSTGHYWM HQPVSFYKLK LTNNTLDQEG HIILHSMHRY LPRLHLVPAE KATEVIQLNG PGVHTFTFPQ TEFFAVTAYQ NIQITQLKID YNPFAKGFRD DGLSSKPQRE GKQRNSSDQE GNSVSSSPAH RVRLTEGEGS EIHSGDFDPV LRGHEASSLS LEKAPHNVKQ DFLGFMNTDS THEVPQLKHE ISESRIVNSF EDDSQISSPS NPNGNFNVVI KEEPLDDYDY ELGECPEGIT VKQEETDEET DVYSNSDDDP ILEKQLKRHN KVDNLEADHP SYKWLPNSPG VAKAKMFKLD AGKMPVVYLE PCAVTKSTVK ISELPDNMLS TSRKDKSMLA ELEYLPAYIE NSDGTDFCLS KDSENSLRKH SPDLRIVQKY TLLKEPNWKY PDILDNSSTE RIHDSSKGST AESFSGKEDL GKKRTTMLKM AIPSKTVTAS HSASPNTPGK RGRPRKLRLS KAGRPPKNTG KSLTAAKNIP VGPGSTFPDV KPDLEDVDGV LFVSFESKEA LDIHAVDGTT EEPSSLQTTT TNDSGCRTRI SQLEKELIED LKSLRHKQVI HPALQEVGLK LNSVDPTVSI DLKYLGVQLP LAPATSFPLW NVTGTNPASP DAGFPFVSRT GKTNDFTKIK GWRGKFQNAS ASRNEGGNSE ASLKNRSAFC SDKLDEYLEN EGKLMETNIG FSSNAPTSPV VYQLPTKSTS YVRTLDSVLK KQSTISPSTS HSVKPQSVTT ASRKTKAQNK QTTLSGRTKS SYKSILPYPV SPKQKNSHVS QGDKITKNSL SSTSDNQVTN LVVPSVDENA FPKQISLRQA QQQHLQQQGT RPPGLSKSQV KLMDLEDCAL WEGKPRTYIT EERADVSLTT LLTAQASLKT KPIHTIIRKR APPCNNDFCR LGCVCSSLAL EKRQPAHCRR PDCMFGCTCL KRKVVLVKGG SKTKHFHKKA ANRDPLFYDT LGEEGREGGG VREDEEQLKE KKKRKKLEYT VCEAEPEQPV RHYPLWVKVE GEVDPEPVYI PTPSVIEPIK PLVLPQPDLS STTKGKLTPG IKPARTYTPK PNPVIREEDK DPVYLYFESM MTCARVRVYE RKKEEQRQLS PPLSPSSSFQ QQSSCYSSPE NRVTKELDSE QTLKQLICDL EDDSDKSQEK SWKSSCNEGE SSSTSYVHQR SPGGPTKLIE IISDCNWEED RNKILSILSQ HINSNMPQSL KVGSFIIELA SQRKCRGEKT PPVYSSRVKI SMPSSQDQDD MAEKSGSETP DGPLSPGKMD DISPVQTDAL DSVRERLHGG KGLPFYAGLS PSGKLVAYKR KPSSTTSGLI QVASNAKVAA SRKPRTLLPS TSNSKMASSG PATNRSGKNL KAFVPAKRPI AARPSPGGVF TQFVMSKVGA LQQKIPGVRT PQPLTGPQKF SIRPSPVMVV TPVVSSEQVQ VCSTVAAAVT TSPQVFLENV TAVPSLTANS DMGAKEATYS SSASTAGVVE ISETNNTTLV TSTQSTATVN LTKTTGITTS PVASVSFAKP LVASPTITLP VASTASTSIV MVTTAASSSV VTTPTSSLSS VPIILSGING SPPVSQRPEN APQIPVTTPQ ISSNNVKRTG PRLLHPNGQI VQLLPLHQIR GSNAQPSLQP VVFRNPGSMV GIRLPAPCKS SETPSSSASS SAFSVMSPVI QAVGSSPTVN VISQAPSLLS SGSSFVSQAG TLTLRISPPE TQNLASKTGS ESKITPSTGG QPVGTASLIP LQSGSFALLQ LPGQKPIPSS VLQHVASLQI KKESQSTDQK DETNSIKREE ETKKALPSKD KALDSEANIM KQNSGIIASE NTSNNSLDDG GDLLDEETLR EDARPYEYSY STGSHTDEDK DGDEDSGNKN QNSPKEKQTV PEVRAGSKNI DIMALQSIRS IRPQKCVKVK VEPQEGSDNP ENPDDFLVLS KDSKFELSGN QVKEQQSNSQ AEAKKDCEDS LGKDSLRERW RKHLKGPLTQ KYIGISQNFN KEANVQFFTE MKPCQENSEQ DISELLGKSG TIESGGVLKT EDGSWSGISS SAAFSIIPRR ATKGRRGSRH FQGHLLLPRE QMKPKQQTKD GRSSAADFTV LDLEDEDEED EKTDDSLDEI VDVVSGYQSE EVDVEKNNYV DYLEDDEQVD VETIEELSEE INFPYKKTTA THTQSFKQQC HSHISADEKA SEKSRKVSLI SSKLKDDCWG DKPHKETEAF AYYRRTHTAN ERRRRGEMRD LFEKLKITLG LLHSSKVSKS LILNRAFSEI QGLTDQADKL IGQKNLLSRK RSILIRKVSS LSGKTEEVVL KKLEYIYAKQ QALEAQKRKK KLGSDEFCVS PRIGTQLEGS SASSVDLGQM LMNNRRGKPL ILSRKRDQAT ENASPSDTPH SSANLVMTPQ GQLLTLKGPL FSGPVVAVSP ALLEGGLKPQ VASSTMSQSE NDDLFMMPRI VNVTSLAAEE DLGGMSGNKY RHEVPDGKPL DHLRDIAGSE ASSLKDTERI SSRGNHRDSR KALGPTQVLL ANKDSGFPHV ADVSTMQAAQ EFIPKNMSGD VRGHRYKWKE CELRGERLKS KESQFHKLKM KDLKDSSIEM ELRKVASAIE EAALHPSELL TNMEDEDDTD ETLTSLLNEI AFLNQQLNDD SGLAELSGSM DTEFSGDAQR AFISKLAPGN RSAFQVGHLG AGVKELPDVQ EESESISPLL LHLEDDDFSE NEKQLGDTAS EPDVLKIVID PEIKDSLVSH RKSSDGGQST SGLPAEPESV SSPPILHMKT GPENSNTDTL WRPMPKLAPL GLKVANPPSD ADGQSLKVMP ALAPIAAKVG SIGHKMNLAG IDQEGRGSKV MPTLAPVVPK LGNSGAPSSS SGK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor.

Gene References into Functions

Loss of Mga expression in two gene-trap alleles results in embryonic lethality PMID:29066359
These results suggest a mechanism whereby Mga influences pluripotent cell survival. PMID:25516968

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Subcellular Location

Nucleus.

Database Links

UNIGENE: Mm.437053

KEGG: mmu:29808

STRING: 10090.ENSMUSP00000106401

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