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Recombinant Mouse Lysosome-associated membrane glycoprotein 5 (Lamp5), partial

Recombinant Mouse Lysosome-associated membrane glycoprotein 5 (Lamp5), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Lamp5

Purity

>85% (SDS-PAGE)

Target Names

Lamp5

Uniprot NO.

Q9D387

Alternative Names

Lamp5Lysosome-associated membrane glycoprotein 5; Brain and dendritic cell-associated LAMP; Brain-associated LAMP-like protein; BAD-LAMP; Lysosome-associated membrane protein 5; LAMP-5

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.

Gene References into Functions

Results show that in mice LAMP5 protein is specifically expressed in subpopulations of GABAergic neurons where it localizes at synaptic terminals, overlapping with VGAT and provide evidence for a fine-tuning function of LAMP5 in evoked GABAergic synaptic transmission. PMID:27272053

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Subcellular Location

Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein. Cell projection, growth cone membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Recycling endosome. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein.

Protein Families

LAMP family

Tissue Specificity

In brain, strongly expressed in the globus pallidus/ventral pallidum complex, the substantia nigra pars reticulata and the entopeduncular nucleus (at protein level). Expressed in the external plexiform layer of the olfactory bulb (at protein level). May b

Database Links

UNIGENE: Mm.41638

KEGG: mmu:76161

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