Home
Product
Protein
Recombinant Proteins
Recombinant Mouse Kinesin-like protein KIF7 (Kif7), partial

Recombinant Mouse Kinesin-like protein KIF7 (Kif7), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Kif7

Uniprot NO.

B7ZNG0

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

1-1348

Target Protein Sequence

MGLEAQRLPG AEEAPVRVAL RVRPLLPKEL LHGHQSCLRV EPERGRITLG RDRHFGFHVV LGEDTGQEAV YQACVQPLLE AFFEGFNATV FAYGQTGSGK TYTMGEASVA SLHEDEQGII PRAMAEAFKL IDENDLLDCL VHVSYLELYK EEFRDLLEVG TASRDIQLRE DDRGNVVLCG VKEVDVEGLD EVLSLLEMGN AARHTGATHF NRLSSRSHTV FTVTLEQRGR TPSRLPRPAA GHLLVSKFHF VDLAGSERVL KTGSTGERLK ESIQINSTLL ALGNVISALG DPQRRGSHIP YRDSKITRIL KDSLGGNAKT VMIACVSPSS SDFDETLNTL NYASRAQNIR NRATVNWHPE AERVPEEQAA GARGPPRHRS ETRIIHRGRR VPCPAVGSAA VAAGLGAECA RCRARTSAAY SLLRELQAEP GLPGAAARKV RDWLCAVEGE RSTLSSASGP DSGIESAPAE DQAAQGTSGR KGDEGTQQLL TLQSQVARLE EENRDFLAAL EDAMEQYKLQ SDRLREQQEE MVELRLRLEL AQPGWGAPGL LQGLPPGSFV PRPHTAPLGG AHTHMLGMMP STCLPGEEVS SEQQVVSGKE VKAEVLAQAD KLRSASSTTS EEEGEEEEEE EEEEEEPPRR TLYLRRNGIS NWSQRAGLSP GSPPDRKGPE VCPEEPAAAI PAPQAVGSGK VPVQTRQAPA AMASEWRLAQ AQQKIRELAI NIRMKEELIG ELVRTGKAAQ ALNRQHSQRI RELEQEAERV RAELCEGQRQ LRELEGREPQ DASERSRLQE FRKRVAAAQS QVQVLKEKKQ ATERLVSLSA QSETRLQELE RNVQLMRRQQ GQLQRRLREE TEQKRRLETE MNKRQHRVKE LELKHEQQQK ILKIKTEEIA AFQRKRRSGS NGSVVSLEQQ QKIEEQKKWL DQEMEKVLQQ RRALEELGEE LRKREVILAK KEALMQEKTG LESKRLRSSQ ALNEDIVRVS SRLEHLEKEL SEKSGQLRQG SAQNQQQIRG EIDTLRQEKD SLLKQRLEID SKLRQGSLLS PEEERTLFQL DEAIEALDAA IEYKNEAITC RQRVLRASAS LLSQCEMNLM AKLSYLSSSE TRALLCKYFD KVVTLREEQH QQQIAFSELE MQLEEQQRLV YWLEVALERQ RLEMDRQLTL QQKEHEQNVQ LLLQQGRDHL GEGLADSKRQ YEARIHALEK ELGRHMWINQ ELKQKLSAGS TAGQSQGCER RSLCLENRQC LGNEDGLHPA APEPLWQSSL LEGVSRVWDE SRDLVHAPLP LTWKRSSLCS EQGSSEESRV RETTEPPVGR VLPMGEVGLS WNFGPLPKPR WEPRRTSPGM IDVRKNPL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms. Involved in the regulation of microtubular dynamics. Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes. Required for localization of GLI3 to cilia in response to Shh. Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand. Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form. In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation. Involved in the regulation of epidermal differentiation and chondrocyte development.

Subcellular Location

Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to the cilium tip.

Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

Tissue Specificity

Expressed in heart, lung, liver, kidney, testis, spleen and cerebellum.

Database Links

UNIGENE: Mm.101633

STRING: 10090.ENSMUSP00000061806

Promotions