Home
Product
Protein
Recombinant Proteins
Recombinant Mouse Interleukin-22 receptor subunit alpha-2 (Il22ra2)

Recombinant Mouse Interleukin-22 receptor subunit alpha-2 (Il22ra2)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

Il22ra2

Purity

>85% (SDS-PAGE)

Target Names

Il22ra2

Uniprot NO.

Q80XF5

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

21-230

Target Protein Sequence

IQPARVSLTP QKVRFQSRNF HNILHWQAGS SLPSNNSIYF VQYKMYGQSQ WEDKVDCWGT TALFCDLTNE TLDPYELYYG RVMTACAGRH SAWTRTPRFT PWWETKLDPP VVTITRVNAS LRVLLRPPEL PNRNQSGKNA SMETYYGLVY RVFTINNSLE KEQKAYEGTQ RAVEIEGLIP HSSYCVVAEM YQPMFDRRSP RSKERCVHIP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.

Gene References into Functions

limits the pathological manifestations in models of allergic contact dermatitis and psoriasis PMID:27676439
Il22bp-deficient mice were more susceptible to acute liver damage in models of acute liver damage induced by ischemia reperfusion and acetaminophen administration. IL-22BP plays a protective role in acute liver damage, via controlling IL-22-induced Cxcl10 expression. PMID:29109123
IL-22BP promotes bacterial uptake into Peyer's patches by influencing follicle-associated epithelium gene expression and function. PMID:28512157
IL22RA2 KO displayed a less severe EAE course, less demyelination and less infiltration of immune cells in the CNS. PMID:25008863
the IL-22-IL-22BP axis critically regulates intestinal tissue repair and tumorigenesis in the colon PMID:23075849
cloning and characterization; gene encodes a protein of 230 amino acids that share 67.1% amino-acid sequence identity with human IL-22 binding protein; upregulated by LPS stimulation in monocytes PMID:12700595