Recombinant Mouse Interleukin-17B (Il17b)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Il17b

Purity

>85% (SDS-PAGE)

Target Names

Il17b

Uniprot NO.

Q9QXT6

Alternative Names

Il17b; Nirf; Zcyto7; Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

23-180

Target Protein Sequence

RNTKGKRK GQGRPSPLAP GPHQVPLDLV SRVKPYARME EYERNLGEMV AQLRNSSEPA KKKCEVNLQL WLSNKRSLSP WGYSINHDPS RIPADLPEAR CLCLGCVNPF TMQEDRSMVS VPVFSQVPVR RRLCPQPPRP GPCRQRVVME TIAVGCTCIF
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.

Gene References into Functions

Interleukin-17B antagonizes interleukin-25-mediated mucosal inflammation. PMID:25888259
expressed in the mouse embryonic limb buds and may play a role in chondrogenesis and osteogenesis PMID:15596145
Socs3 is an essential negative regulator of IL-23 signaling, inhibition of which constrains the generation of IL-17-secreting T-cell differentiation PMID:16698929
IL-17B and IL-17C play an important role in the pathogenesis of inflammatory arthritis. PMID:17982105