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Recombinant Mouse Interleukin-17 receptor B (Il17rb), partial

Recombinant Mouse Interleukin-17 receptor B (Il17rb), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Il17rb

Purity

>85% (SDS-PAGE)

Target Names

Il17rb

Uniprot NO.

Q9JIP3

Alternative Names

Il17rb; Evi27; Il17br; Interleukin-17 receptor B; IL-17 receptor B; IL-17RB; IL-17 receptor homolog 1; IL-17ER; IL-17Rh1; IL17Rh1; Interleukin-17B receptor; IL-17B receptor

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.

Gene References into Functions

IL-17E (IL-25) and IL-17RB promote respiratory syncytial virus-induced pulmonary disease PMID:24407884
Results show that amplified signaling of interleukin-17 receptor B (IL-17RB) and its ligand IL-17B promot tumorigenicity in breast cancer cells and impeded acinus formation in immortalized normal mammary epithelial cells. PMID:23851503
data establish IL-25 and its receptor IL-17RB as targets for innate and adaptive immune responses in chronic allergic airway disease and identify T2M cells as a new steroid-resistant cell population PMID:22543263
IL-25-mediated activities require both IL-17RB and IL-17RA in this example of an IL-17 family ligand that utilizes a heteromeric receptor complex. PMID:18768888
Results identify a novel subset of natural killer T cells that expresses the interleukin 17 receptor B (IL-17RB) for IL-25 and is essential for the induction of the airway hypersensitive reaction. PMID:19015310
IL-17RB(+) iNKT cells were detected in the lungs of wild-type mice, and induction of airway hyperreactivity by intranasal administration of IL-25 was significantly impaired in iNKT cell-deficient mice PMID:19342692
IL-17RB-positive cells in the bone marrow also express CD11B, GR1, and c-kit, potentially suggesting a maturation of the bone marrow cell once it enters the inflamed lung. PMID:19828636