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Recombinant Mouse Heparan-sulfate 6-O-sulfotransferase 2 (Hs6st2), partial

Recombinant Mouse Heparan-sulfate 6-O-sulfotransferase 2 (Hs6st2), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Hs6st2

Purity

>85% (SDS-PAGE)

Target Names

Hs6st2

Uniprot NO.

Q80UW0

Alternative Names

Hs6st2; Heparan-sulfate 6-O-sulfotransferase 2; HS6ST-2; mHS6ST-2; EC 2.8.2.-

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.

Gene References into Functions

Overexpression or silencing of HS6ST2 significantly enhanced or abrogated the effects of fibroblast growth factor (FGF)2 on chondrocyte growth, respectively. PMID:26133911
Hs6st2 knockout mice had increased body weight, insulin resistance and high thyroid hormone level. PMID:23690091
Results indicate that HS6ST2 gene influences expression of genes linked to aggrecan metabolism and is implicated in pathogenesis of osteoarthritis. PMID:21972422
6OST2 is more mesenchymal than its isoenzymes during development PMID:15499561