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Recombinant Mouse Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas (Gnas), partial

Recombinant Mouse Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas (Gnas), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Gnas

Purity

>85% (SDS-PAGE)

Target Names

Gnas

Uniprot NO.

Q6R0H7

Alternative Names

Gnas; Gnas1Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Adenylate cyclase-stimulating G alpha protein; Extra large alphas protein; XLalphas

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

1-1133

Target Protein Sequence

MGMFNCLHGN NMSGQHDIPP EVGEQPEQEP LEAPGAAAPG AGAGPAEEMA TEPDSEPSNN EPVPDETGSE ISGPPEDSKS DIQSPCQAFE EVRVGGDYSP PPEEAMPFET QQPSLGDFWP TLEQPGPSGT PSGLQAFNPA ILEPGTPTGA SPGLGAYTPP PEEAMPFEFN EPAQGDHSQP PLQVPDLAPG GPEALVPRAL PAEPGNIRFE NAGFREDYSP PPEESVPFQV GGEEFGGDSP PPGLPRVIPQ IGIGGEFPTV AVPSALCLAP AENAPPLWVR GAIDRPFREA VRSPPNFACD SPPMEITRPL LEIGRASIGV DDDTAVNMDS PPIASDGPPI EVSGAPDKSE CAERPPVERE AAEMEGSPTT ATAVEGKVPS PERGDGSSTQ PEAMDAKPAP AAQAVSTGSD AGAPTDSAML TDSQSDAGED GTAPGTPSDL QSDPEELEEA PAVRADPDGG AAPVAPATPA ESESEGSRDP AAEPASEAVP ATTAESASGA APVTQVEPAA AAVSATLAEP AARAAPITPK EPTTRAVPSA RAHPAAGAVP GAPAMSASAR AAAARAAYAG PLVWGARSLS ATPAARASLP ARAAAAARAA SAARAVAAGR SASAAPSRAH LRPPSPEIQV ADPPTPRPPP RPTAWPDKYE RGRSCCRYEA SSGICEIESS SDESEEGATG CFQWLLRRNR RPGLPRSHTV GSNPVRNFFT RAFGSCFGLS ECTRSRSLSP GKAKDPMEER RKQMRKEAIE MREQKRADKK RSKLIDKQLE EEKMDYMCTH RLLLLGAGES GKSTIVKQMR ILHVNGFNGE GGEEDPQAAR SNSDGEKATK VQDIKNNLKE AIETIVAAMS NLVPPVELAN PENQFRVDYI LSVMNVPNFD FPPEFYEHAK ALWEDEGVRA CYERSNEYQL IDCAQYFLDK IDVIKQADYV PSDQDLLRCR VLTSGIFETK FQVDKVNFHM FDVGGQRDER RKWIQCFNDV TAIIFVVASS SYNMVIREDN QTNRLQEALN LFKSIWNNRW LRTISVILFL NKQDLLAEKV LAGKSKIEDY FPEFARYTTP EDATPEPGED PRVTRAKYFI RDEFLRISTA SGDGRHYCYP HFTCAVDTEN IRRVFNDCRD IIQRMHLRQY ELL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as Gnas isoforms.

Subcellular Location

Cell membrane; Peripheral membrane protein. Apical cell membrane.

Protein Families

G-alpha family, G(s) subfamily

Database Links

UNIGENE: Mm.125770

STRING: 10090.ENSMUSP00000079341

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