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Recombinant Mouse Glycylpeptide N-tetradecanoyltransferase 1 (Nmt1)

Recombinant Mouse Glycylpeptide N-tetradecanoyltransferase 1 (Nmt1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Nmt1

Uniprot NO.

O70310

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

1-496

Target Protein Sequence

MADESETAVK LPAPSLPLMM EGNGNGHEHC SDCENEEDNS HNRSGLSPAN DTGAKKKKKK QKKKKEKGSD MESTQDQPVK MTSLPAERIQ EIQKAIELFS VGQGPAKTME EASKRSYQFW DTQPVPKLGE VVNTHGPVEP DKDNIRQEPY TLPQGFTWDA LDLGDRGVLK ELYTLLNENY VEDDDNMFRF DYSPEFLLWA LRPPGWLPQW HCGVRVVSSR KLVGFISAIP ANIHIYDTEK KMVEINFLCV HKKLRSKRVA PVLIREITRR VHLEGIFQAV YTAGVVLPKP VGTCRYWHRS LNPRKLIEVK FSHLSRNMTM QRTMKLYRLP ETPKTAGLRP MEKKDIPVVH QLLSRYLKQF HLTPVMNQEE VEHWFYPQEN IIDTFVVENA NGEVTDFLSF YTLPSTIMNH PTHKSLKAAY SFYNVHTQTP LLDLMSDALV LAKMKGFDVF NALDLMENKT FLEKLKFGIG DGNLQYYLYN WKCPSMGAEK VGLVLQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Required for normal embryogenesis.

Gene References into Functions

Nmt1 is not essential for the viability of mammalian cells but is required for development and is the principal N-myristoyltransferase in early embryogenesis PMID:15753093
NMT1 and NMT2 have only partially overlapping functions; NMT1 is critical for tumor cell proliferation PMID:16123142
NMT1 is essential for proper monocytic differentiation of the mouse bone marrow cells. PMID:18178842

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Subcellular Location

Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein.

Protein Families

NMT family

Tissue Specificity

Ubiquitous.

Database Links

UNIGENE: Mm.10265

KEGG: mmu:18107

STRING: 10090.ENSMUSP00000021314

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