Recombinant Mouse Galectin-3 (Lgals3)

Baculovirus

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Lgals3

Uniprot NO.

P16110

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

2-264

Target Protein Sequence

ADSFSLNDA LAGSGNPNPQ GYPGAWGNQP GAGGYPGAAY PGAYPGQAPP GAYPGQAPPG AYPGQAPPSA YPGPTAPGAY PGPTAPGAYP GQPAPGAFPG QPGAPGAYPQ CSGGYPAAGP YGVPAGPLTV PYDLPLPGGV MPRMLITIMG TVKPNANRIV LDFRRGNDVA FHFNPRFNEN NRRVIVCNTK QDNNWGKEER QSAFPFESGK PFKIQVLVEA DHFKVAVNDA HLLQYNHRMK NLREISQLGI SGDITLTSAN HAMI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

Subcellular Location

Cytoplasm. Nucleus. Secreted.

Tissue Specificity

The highest levels are found in activated macrophages.

Database Links

UNIGENE: Mm.248615

STRING: 10090.ENSMUSP00000114350

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