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Recombinant Mouse Enhancer of mRNA-decapping protein 4 (Edc4), partial

Recombinant Mouse Enhancer of mRNA-decapping protein 4 (Edc4), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Edc4

Purity

>85% (SDS-PAGE)

Target Names

Edc4

Uniprot NO.

Q3UJB9

Alternative Names

Edc4Enhancer of mRNA-decapping protein 4

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

2-1406

Target Protein Sequence

ASCASIDIE DATQHLRDIL KLDRPAGGSN AESQRPSSAY NGDLNGLLVP DPLSSGDGNS TNKPGIRTMP PINLQEKQVI CLSGDDSSTC IGILAKEVEI VASSDSSISS KARGSNKVKI QPVAKYDWEQ KYYYGNLIAV SNSFLAYAIR AANNGSAMVR VISVSTSERT LLKGFTGSVA DLAFAHLNSP QLACLDEAGN LFVWRLALVK GKIQEEILVH IRQPEGTALN HFRRIIWCPF IPEESEDCCE ESSPTVALLH EDRAEVWDLD MLRSSHNTWP VDVSQIKQGF IVVKGHSTCL SEGALSPDGT VLATASHDGF VKFWQIYIEG QDEPRCLHEW KPHDGRPLSC LLFCDNHKKQ DPEVPFWRFL ITGADQNREL KMWCTVSWTC LQTIRFSPDI FSSVSVPPSL KVCLDLSAEY LILSDVQRKV LYVMELLQNQ DEGRACFSSI SEFLLTHPVL SFGIQVVSRC RLRHTEVLPA EEENDSLGTE SSHGAGALES AAGVLIKLFC VHTKALQDVQ IRFQPQLNPD VVAPLSTHTA HEDFTFGESR PELGSEGLAS AAHGSQPDLR RIVELPAPAD FLSLSSETKP ELMTPDAFMT PTASLQQISA SPSSSSSSSS SSSSSSSSSS SSLTAVSAVS SSSAMDPSLP RPPEELTLSP KLQLDGSLTL NSSSSSLQAS PRSLLPGLLP GPADKLISKG PGQVSTAASA LSLDLQEVEP LGLPQASPSR TRSPDVISSA STALSQDIPE IASEALSRGF GSSVPEGLIE PNSMASAASA LHLLSPRPRQ GPELGSQLGL DGGPGDGDRH STPSLLEAAL TQEVATPDSQ VWPTAPDITR ETCSTLTESP RNGLQEKHKS LAFHRPPYHL LQQRDSQDTS AEQSDHDDEV ASLASASGGF GSKIPTPRLP SKDWKTKGSP RTSPKLKRKS KKDDGDSAVG SRLTEHQVAE PPEDWPALIW QQQRELAELW HNQEELLQRL CAQLEGLQST VTDHVERALE TRHEQEQRRL ERALAEGQQR GGQLQEQLTQ QLSQALSSAV AGRLERSVRD EIKKTVPPCV SRSLEPVAGQ LSNSVATKLT AVEGSMKENI SKLLKSKNLT DAIARAAADT LQGPMQAAYR EAFQSVVLPA FEKSCQAMFQ QINDSFRLGT QEYLQQLESH MKSRKAREQE AREPVLAQLR GLVSTLQSAT EQMAATVSSS VRAEVQHQLH VAVGSLQESI LAQVQRIVKG EVSVALKEQQ ATVTSSIMQA MRSAAGTPVP SAHLDCQAQQ AHILQLLQQG HLNQAFQQAL TAADLNLVLY VCETVDPAQV FGQPPCPLSQ PVLLSLIQQL ASDLGTRSDL KLSYLEEAVM HLDHSDPITR DHMGSVMAQV RQKLFQFLQA DPHNSLSKAA RRLSLMLHGL VTPSLP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).

Gene References into Functions

Ge-1, the human ortholog of mouse Edc4, was shown to localize to mRNA processing bodies (P-body)in a human cell line. The C-terminal region is required for this localization. PMID:16314453
The human Ge-1 gene (also known as Hedls and Edc4)is an ortholog of mouse Edc4. The gene was identified by screening a cDNA expression library using serum from a patient with Sjogren's syndrome. PMID:7520377

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Subcellular Location

Cytoplasm, P-body. Nucleus.

Protein Families

WD repeat EDC4 family

Database Links

UNIGENE: Mm.28979

KEGG: mmu:234699

STRING: 10090.ENSMUSP00000113854

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