Recombinant Mouse Cysteine protease ATG4A (Atg4a)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Atg4a

Purity

>85% (SDS-PAGE)

Target Names

Atg4a

Uniprot NO.

Q8C9S8

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

1-396

Target Protein Sequence

MESVMSKYEN QILIFPDYLE EFPDTDELVW ILGKQHPLKT EKSKLLSDIS ARLWFTYRRK FSPIGGTGPS SDAGWGCMLR CGQMMLAQAL ICRHLGRDWN WERQKEQPKE YQRILQCFLD RKDCCYSIHQ MAQMGVGEGK SIGEWFGPNT VAQVIKKLAL FDEWNSLAVY VSMDNTVVIE DIKKMCCVLP VGAADPAGDF LTASNQSRDT SVPCSAWKPL LLIVPLRLGI NQINPVYVEA FKECFKMPQS LGALGGKPNN AYYFIGFLGD ELIFLDPHTT QTFVDIEESG LVDDQTFHCL QSPQRMSILN LDPSVALGFF CKEEKDFDNW CSLVQKEILK ENLRMFELVQ KHPSHWPPFV PPAKPEVTTT GAEFIESTEQ LEDFELEEDF EILSVG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Subcellular Location

Cytoplasm.

Protein Families

Peptidase C54 family

Database Links

UNIGENE: Mm.102230

KEGG: mmu:666468

STRING: 10090.ENSMUSP00000108595

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