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Recombinant Mouse Collagen alpha-4 (IV) chain (Col4a4), partial

Recombinant Mouse Collagen alpha-4 (IV) chain (Col4a4), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Col4a4

Purity

>85% (SDS-PAGE)

Target Names

Col4a4

Uniprot NO.

Q9QZR9

Alternative Names

Col4a4Collagen alpha-4(IV) chain

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

33-1682

Target Protein Sequence

KKYGGPCG GRNCSVCQCF PEKGSRGHPG PLGPQGPIGP LGPLGPIGIP GEKGERGDSG SPGPPGEKGD KGPTGVPGFP GVDGVPGHPG PPGPRGKPGV DGYNGSRGDP GYPGERGAPG PGGPPGQPGE NGEKGRSVYI TGGVKGIQGD RGDPGPPGLP GSRGAQGSPG PMGHAGAPGL AGPIGHPGSP GLKGNPATGL KGQRGEPGEV GQRGPPGPTL LVQPPDLSIY KGEKGVKGMP GMIGPPGPPG RKGAPGVGIK GEKGIPGFPG PRGEPGSHGP PGFPGFKGIQ GAAGEPGLFG FLGPKGDLGD RGYPGPPGIL LTPAPPLKGV PGDPGPPGYY GEIGDVGLPG PPGPPGRPGE TCPGMMGPPG PPGVPGPPGF PGEAGVPGRL DCAPGKPGKP GLPGLPGAPG PEGPPGSDVI YCRPGCPGPM GEKGKVGPPG RRGAKGAKGN KGLCTCPPGP MGPPGPPGPP GRQGSKGDLG LPGWHGEKGD PGQPGAEGPP GPPGRPGAMG PPGHKGEKGD MVISRVKGQK GERGLDGPPG FPGPHGQDGG DGRPGERGDP GPRGDHKDAA PGERGLPGLP GPPGRTGPEG PPGLGFPGPP GQRGLPGEPG RPGTRGFDGT KGQKGDSILC NVSYPGKPGL PGLDGPPGLK GFPGPPGAPG MRCPDGQKGQ RGKPGMSGIP GPPGFRGDMG DPGIKGEKGT SPIGPPGPPG SPGKDGQKGI PGDPAFGDPG PPGERGLPGA PGMKGQKGHP GCPGAGGPPG IPGSPGLKGP KGREGSRGFP GIPGSPGHSC ERGAPGIPGQ PGLPGTPGDP GAPGWKGQPG DMGPSGPAGM KGLPGLPGLP GADGLRGPPG IPGPNGEDGL PGLPGLKGLP GLPGFPGFPG ERGKPGPDGE PGRKGEVGEK GWPGLKGDLG ERGAKGDRGL PGDAGEAVTS RKGEPGDAGP PGDGGFSGER GDKGSSGMRG GRGDPGRDGL PGLHRGQPGI DGPPGPPGPP GPPGSPGLRG VIGFPGFPGD QGDPGSPGPP GFPGDDGARG PKGYKGDPAS QCGPPGPKGE PGSPGYQGRT GVPGEKGFPG DEGPRGPPGR PGQPGSFGPP GCPGDPGMPG LKGHPGEVGD PGPRGDAGDF GRPGPAGVKG PLGSPGLNGL HGLKGEKGTK GASGLLEMGP PGPMGMPGQK GEKGDPGSPG ISPPGLPGEK GFPGPPGRPG PPGPAGAPGR AAKGDIPDPG PPGDRGPPGP DGPRGVPGPP GSPGNVDLLK GDPGDCGLPG PPGSRGPPGP PGCQGPPGCD GKDGQKGPMG LPGLPGPPGL PGAPGEKGLP GPPGRKGPVG PPGCRGEPGP PADVDSCPRI PGLPGVPGPR GPEGAMGEPG RRGLPGPGCK GEPGPDGRRG QDGIPGSPGP PGRKGDTGEA GCPGAPGPPG PTGDPGPKGF GPGSLSGFLL VLHSQTDQEP ACPVGMPRLW TGYSLLYMEG QEKAHNQDLG LAGSCLPVFS TLPFAYCNIH QVCHYAQRND RSYWLSSAAP LPMMPLSEEE IRSYISRCAV CEAPAQAVAV HSQDQSIPPC PRTWRSLWIG YSFLMHTGAG DQGGGQALMS PGSCLEDFRA APFVECQGRQ GTCHFFANEY SFWLTTVNPD LQFASGPSPD TLKEVQAQRR KISRCQVCMK HS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.

Gene References into Functions

the NC1 domain of {alpha}3 chain is critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly PMID:20847057
In kidney, when expressed onto Col4a3(-/-) background, human alpha3(IV) chain restored expression of and co-assembled with mouse alpha4 and alpha5(IV) chains at sites where human alpha3(IV) was expressed. All three chains required for network assembly. PMID:14507670

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Subcellular Location

Secreted, extracellular space, extracellular matrix, basement membrane.

Protein Families

Type IV collagen family

Tissue Specificity

Expressed in Bruch's membrane, outer plexiform layer, inner nuclear layer, inner plexiform layer, ganglion cell layer, inner limiting membrane and around the blood vessels of the retina (at protein level). Highly expressed in kidney and lung. Detected at

Database Links

UNIGENE: Mm.40253

KEGG: mmu:12829

STRING: 10090.ENSMUSP00000084282

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