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Recombinant Mouse Collagen alpha-1 (XI) chain (Col11a1), partial

Recombinant Mouse Collagen alpha-1 (XI) chain (Col11a1), partial

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Col11a1

Purity

>85% (SDS-PAGE)

Target Names

Col11a1

Uniprot NO.

Q61245

Alternative Names

Col11a1Collagen alpha-1(XI) chain

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

512-1561

Target Protein Sequence

AQAQAILQQ ARIALRGPPG PMGLTGRPGP VGGPGSAGAK GESGDPGPQG PRGVQGPPGP TGKPGKRGRP GADGGRGMPG ESGSKGDRGF DGLPGLPGDK GHRGERGPQG PPGLPGDDGM RGEDGEIGPR GLPGEAGPRG LLGPRGTPGP PGQPGIGGID GPQGPKGNMG PQGEPGPPGQ QGNPGPQGLP GPQGPIGPPG EKGPQGKPGL AGLPGADGPP GHPGKEGQSG EKGALGPPGP QGPIGYPGPR GVKGADGVRG LKGSKGEKGE DGFPGFKGDM GLKGDRGEVG QVGPRGEDGP EGPKGRAGPT GDPGPSGQAG EKGKLGVPGL PGYPGRQGPK GSTGFPGFPG ANGEKGARGI AGKPGPRGQR GPTGPRGSRG ARGPTGKPGP KGTSGGDGPP GPPGERGPQG PQGPVGFPGP KGPPGPAGKD GLPGHPGQRG ETGFQGKTGP PGPGGVVGPQ GPTGETGPIG ERGHPGPPGP PGEQGLPGAA GKEGAKGDPG PQGISGKDGP AGIRGFPGER GLPGAQGAPG LKGGEGPQGP QGPVGSPGER GSAGTAGPIG LPGRPGPQGP PGPAGEKGAP GEKGPQGPAG RDGVQGPVGL PGPAGPAGSP GEDGDKGEIG EPGQKGSKGD KGENGPPGPP GLQGPVGAPG IAGGDGEPGP RGQQGMFGQK GDEGARGFPG LPGPIGLQGL PGPPGEKGEN GDVGPMGPPG PPGPRGPQGP NGADGPQGPP GSIGSVGVVG DKGEPGEAGN PGPPGEAGSG GLKGERGEKG EAGPPGAAGP AGIKGPPGDD GPKGNPGPVG FPGDPGPPGE PGPAGQDGVG GDKGEDGDPG QPGPPGPSGE AGPPGPPGKR GPPGASGSEG RQGEKGAKGE AGAEGPPGKT GPVGPQGPSG KPGPEGLRGI PGPVGEQGLP GAAGQDGPPG PLGPPGLPGL KGDPGSKGEK GHPGLIGLIG PPGEQGEKGD RGLPGTQGSP GAKGDGGIPG PAGPIGPPGP PGLPGPAGPK GNKGSSGPTG QKGDSGMPGP PGPPGPPGEV IQPLPILSPK KTRRHTESIQ G
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.

Gene References into Functions

Taken together, these results indicate that the transcription factor Sp1 upregulates the proximal promoter activity of the mouse Col11a1 gene in chondrocytes. PMID:26487428
these results indicate that the transcription factor NF-Y regulates the proximal promoter activity of mouse Col11a1 gene in chondrocytes PMID:24092017
Stickler syndrome and Marshall syndrome mutations in COL11A1 cause hearing loss via dominant negative effects upon wild-type fibrillar collagen polypeptides in the extracellular matrices of the cochlea. PMID:12527136
the cho mutation leads to osteoarthritis through a mechanism that does not initially involve mechanical factors. PMID:13130470
The expression patterns suggest essential roles for Col11a1 and Col11a2 in the basilar or tectorial membranes. PMID:15141750
Lef1 is an activator of the Col11a1 promoter and that Col11a1 suppresses terminal osteoblast differentiation PMID:18280717