Recombinant Mouse Carbonic anhydrase 1 (Ca1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Ca1

Uniprot NO.

P13634

Alternative Names

Ca1; Car1Carbonic anhydrase 1; EC 4.2.1.1; Carbonate dehydratase I; Carbonic anhydrase I; CA-I

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

2-261

Target Protein Sequence

ASADWGYGS ENGPDQWSKL YPIANGNNQS PIDIKTSEAN HDSSLKPLSI SYNPATAKEI VNVGHSFHVI FDDSSNQSVL KGGPLADSYR LTQFHFHWGN SNDHGSEHTV DGTRYSGELH LVHWNSAKYS SASEAISKAD GLAILGVLMK VGPANPSLQK VLDALNSVKT KGKRAPFTNF DPSSLLPSSL DYWTYFGSLT HPPLHESVTW VICKDSISLS PEQLAQLRGL LSSAEGEPAV PVLSNHRPPQ PLKGRTVRAS F
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Reversible hydration of carbon dioxide.

Gene References into Functions

During inner ear development, transcripts of four cytosolic isozymes (Car1, Car2, Car3, and Car13), two membrane-bound isozymes (Car12 and Car14), and two CA-related proteins (Car8 and Car11) were expressed at higher levels than other isozymes. PMID:23233153
Over-expression of CA1 may aggravate joint inflammation and tissue destruction in the transgenic mice. PMID:23256642
Taken together, these data show that Ldb1 forms a regulatory complex to maintain Car1 expression in erythroid cells. PMID:22609543
Regulatory dendritic cells pulsed with carbonic anhydrase I suppress development of colitis in a severe combined immunodeficiency (SCID) mouse transfer model by inducing the differentiation of regulatory T cells in an antigen-specific manner. PMID:22291189