Recombinant Mouse CAMPATH-1 antigen (Cd52)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Cd52

Purity

>85% (SDS-PAGE)

Target Names

Cd52

Uniprot NO.

Q64389

Alternative Names

Cd52; Cdw52; Mb7CAMPATH-1 antigen; Lymphocyte differentiation antigen B7; CD antigen CD52

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

24-47

Target Protein Sequence

GQATTAA SGTNKNSTST KKTPLKS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Cytoplasmic domain

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

May play a role in carrying and orienting carbohydrate, as well as having a more specific role.

Gene References into Functions

Soluble CD52 is used by certain CD4-positive cells to suppress target celss via the inhibitory receptor Siglec-10. PMID:23685786
expression is induced in the mouse uterus at the time of embryo implantation PMID:19735946
Genetic background determines the requirement for B7 costimulation in autoimmunity induction. Backcrossed B7.1/B7.2 deficient (-/-)mice on C57BL/6 (B6) or SJL backgrounds had different susceptibility to induced experimental autoimmune encephalomyelitis. PMID:12207354
study examined the tissue distribution, molecular composition and immunogenicity of mouse male reproductive tract-CD52 PMID:17418902
The results indicate CD52 is not required for fertilization in the mouse either in vivo or in vitro. PMID:18782223
Study helps to precisely define CD52 expression in the tumor cell population of PTCL and might therefore be valuable when evaluating the response to alemtuzumab therapy in prospective clinical trials. PMID:19479612