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Recombinant Mouse Adhesion G protein-coupled receptor B3 (Adgrb3), partial

Recombinant Mouse Adhesion G protein-coupled receptor B3 (Adgrb3), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Bai3

Purity

>85% (SDS-PAGE)

Target Names

Adgrb3

Uniprot NO.

Q80ZF8

Alternative Names

Adgrb3; Bai3Adhesion G protein-coupled receptor B3; Brain-specific angiogenesis inhibitor 3

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Buffer

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1.

Gene References into Functions

Signal transduction via C1qL1-BAI3 interaction is required for motor learning, triggers pruting of surplus cerebellar climbing fibers, and is required to maintain climbing fiber synapses. PMID:25611509
G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates. PMID:24567399
results reveal that the BAI3 receptor controls dendritic arborization growth and branching in cultured neurons. PMID:23628982
Two transcripts with significant regulation from days 7 to 28 in the 1-methyl-4-phenyl-tetrahydropyridine treated groups are identified: brain specific angiogenesis inhibitor associated protein 3 (Baiap3) and breast carcinoma amplified sequence 1 (Bcas1). PMID:21514331
C1ql proteins are secreted signaling molecules that bind to BAI3 and act, at least in part, to regulate synapse formation and/or maintenance. PMID:21262840