Recombinant Mouse Amphiphysin (Amph)

Product Details

Abbreviation
Amph
Purity
>85% (SDS-PAGE)
Target Names
Amph
Uniprot NO.
Alternative Names
Amph; Amph1Amphiphysin
Species
Mus musculus (Mouse)
Source
Yeast
Expression Region
1-686
Target Protein Sequence
MADIKTGIFA KNVQKRLNRA QEKVLQKLGK ADETKDEQFE EYVQNFKRQE AEGTRLQREL RGYLAAIKGM QEASMKLTES LHEVYEPDWY GREDVKMVGE KCDVLWEDFH QKLVDGSLLT LDTYLGQFPD IKNRIAKRSR KLVDYDSARH HLEALQSSKR KDESRISKAE EEFQKAQKVF EEFNVDLQEE LPSLWSSRVG FYVNTFKNVS SLEAKFHKEI AVLCHKLYEV MTKLGDQHAD KAFSIQGAPS DSGPLRIAKT PSPPEEPSPL PSPTASPNHT LAPASPAPVR PRSPSQTRKG PPVPPLPKVT PTKELKQENI INFFEDNFVP EINVTTPSQN EVLEVKKEET LLDLDFDPFK PDVAPAGSAA ATHSPMSQTL PWDLWTTSTD LVQPASGGSF NDFTQAQDTS LFTMQTDQNM AETEQALPTE PQAEEPPATA AAPTAGLDLG LEMEEPKEEA VIPPATDTGE TVETAVPTEG APVEEAEAEK AALPAGEGGS PEGAKIDGES TELAISESPQ PVEPEAGAPQ VIPSVVIEPA SNHEGEGEHQ ETATGTEPRE AAEDVAAQGS AGEKQEVATE PTPLDSQATL PASAGAVDAS LSAGDATQEL PPGFLYKVET LHDFEAANSD ELNLQRGDVV LVVPSDSEAD QDAGWLVGVK ESDWLQYRDL ATYKGLFPEN FTRRLE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
Gene References into Functions
  1. Amph1 is the cytoplasmic substrate for CDKL5 and that its phosphorylation may play crucial roles in the neuronal development. PMID:23651931
  2. amphiphysin IIm has a role in survival of Chlamydia pneumoniae in macrophages PMID:15337791
  3. calpain-dependent cleavage of amphiphysin I inhibits synaptic vesicle endocytosis during neural hyperexcitation and demonstrate a novel post-translational regulation of endocytosis PMID:17541403
  4. results suggest that amphiphysin 1 and dynamin 2 are involved in TBC formation and spermatid release at Sertoli cells PMID:17785912
  5. amphiphysin 1 is important in the regulation of actin dynamics PMID:17855509
  6. As amphiphysin is involved in the regulation of endocytosis, phosphorylation at this site may play a role in the regulated re-uptake of synaptic vesicles after neurotransmitter release. PMID:18761055

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Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Database Links
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