Home
Product
Protein
Recombinant Proteins
Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 18 (Adamts18), partial

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 18 (Adamts18), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

Adamts18

Purity

>85% (SDS-PAGE)

Target Names

Adamts18

Uniprot NO.

Q4VC17

Alternative Names

Adamts18A disintegrin and metalloproteinase with thrombospondin motifs 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18; EC 3.4.24.-

Species

Mus musculus (Mouse)

Source

Yeast

Expression Region

48-1219

Target Protein Sequence

SDS GSSGGSGLND DYVFVVPVEV DSGGSYISHD ILHHRKRRSA HGASNSLHYR VSAFGQDLHL ELKPSAILSS HFRVQVLGKD GASETREPEV PQCLYQGFIR NDSSSSVAVS TCAGLSGLIR TRDNEFLISP LPQLLAQEHN YSSPAGHHPH VLYKRTAEKR VRWYQDYPGS QRTYPGHSPS HTPPASQSQE PEYSHRRWQK RHFCGRRKKY APKPPAEDAY LRFDEYGGTG RPRRSAGKSQ NGLNVETLVV ADAKMVEKHG KDDVTTYILT VMNMVSSLFK DGTIGSDINI VVVSLILLEE EPEGLLINHH ADQSLNSFCQ WQSALVGKNG KRHDHAILLT GFDICSWKNE PCDTLGFAPI SGMCSKYRSC TINEDTGLGL AFTIAHESGH NFGMVHDGEG NPCRKAEGNI MSPTLTGNNG VFSWSSCSRQ YLKKFLSTPQ AGCLVDEPKQ TGQYKYPDKL PGQIYDADMQ CKWQFGAKAK LCSLGVMKDI CKSLWCHRVG HRCETKFMPA AEGTACGLSM WCRQGQCVKL GELGPRPIHG QWSAWSKWSE CSRTCGGGVK FQERHCSNPK PQYGGKYCPG SSRIYKLCNI NPCPENSLDF RAQQCAEYNN KPFRGWLYRW KPYTKVEEED RCKLYCKAEN FEFFFAMSGK VKDGTPCSPH RNDVCIDGIC ELVGCDHELG SKAVSDACGV CKGDNSTCKF YKGLYLSQHK ANEYYPVVTI PAGARSIEIQ ELQLSSSYLA VRSLSQKYYL TGGWSIDWPG DFTFAGTTFE YQRSFNRPER LYAPGPTNET LVFEILTQGK NPGIAWKYAL PKVMNVTQPA TKRYHHTWRT VQSDCSVTCG GGYISIKAIC LRDQHTQVNS SFCSVRTKPA TEPKICNAFS CPAYWLPGEW SACSKSCAGG QQSRKIRCVQ KKPFQKEEAV LHSLCPVSTP TQVQVCNSHA CPPEWSPSPW SQCSKTCGRG VRRREVLCKS PAAETLPESL CSSSPRPEAQ EGCVLGRCPK NNRLQWIASA WSECSATCGL GVRKRELKCV EKTLQGKLIT FPERRCRNIK KPSLELEEAC NQRTCPVYSM AVASWYSSPW QQCTVTCGGG VQTRSVHCMQ QGRPSSSCLL HQKPPVLRAC NTNFCPAPEK KDDPSCVDFF SWCHLVPQHG VCNHKFYGKQ CCRSCTRKS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Gene References into Functions

The underlying molecular mechanisms could be attributed in part to the abnormal vascular remodeling, including deficiency of carotid body (glomus) and aberrant carotid basal lamina. These results indicate a novel function of ADAMTS18 in vascular remodeling and associated thrombus formation. PMID:29421655
Adamts18 deficiency enhances tumorigenesis and intestinal inflammation through elevated Wnt/beta-catenin and p38MAPK/ERK1/2 signaling and promotes colon cancer in a mouse model. PMID:28145888
these data demonstrate a thrombin cleavage site and confirm a short form of ADAMTS-18 presents in vivo. PMID:22386991
Adamts18 is expressed in the lens and retina in the developing murine eye. PMID:21862674