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Recombinant Methanosarcina mazei DNA double-strand break repair Rad50 ATPase (rad50), partial

Recombinant Methanosarcina mazei DNA double-strand break repair Rad50 ATPase (rad50), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

rad50

Purity

>85% (SDS-PAGE)

Target Names

rad50

Uniprot NO.

Q8PUY4

Alternative Names

rad50; MM_2194; DNA double-strand break repair Rad50 ATPase

Species

Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)

Source

Yeast

Expression Region

1-1070

Target Protein Sequence

MKLKNLYIEN IRSYKKLDFT FEDGVTVISG VNGSGKSSLL EACFMGLFGS KILSKDFVLA DMIFKGAESA KIHLGFEHLG REYLIEQAFR YSLKSENASN SRCVLFADGE NIVDQATRTY EEVCALLNMD EEAYRNCAYI RQGEIDVLIN AKPRDRQRMI DDLLQLGKLE EYRERAGYAK TAVRRLERDA KNSFLGVKAE IEGIESTEPV AAVNRLRQKV KETDAILEEL NKKKEFAAAR KGELDLRIAE YRERLQEIEV LKQAIRKSQE DKAACFKEKE TFSEEVQVQR RVLLELGEEN SGMREECGFG DLEIEALLLQ QEKSESSARE KVNSGSKELA LLLKEEETGV QALRELEKDK VETERVLVEC RTSIGAANKE IEGYRANIKQ LEEENKRLRE KAGFGAAGEI ASVIKELEEK ESLLRDRKNE VSTKLGFALK EKESGDASLR ELDSEMQSCR VAVSKGKSEI EALEKEIRDN SKAVLDFQEQ KSEVFAGLKA LGFTEEQLEN LEDFNELLLE NKNRLHGKEK ELEVTLREIE NTLRKNRELL AEGKCPTCGQ ELKGSGIACT AEECEEKKEK LSLELADIKL QRAELEKKLN RLKEAKKLEK QAYDYDIEIE KLLEKAKASE KLIDTHRTRI EEDSLKLESS GKRKQELEAA GSKLLLDIKA LREQEKAAQK VHLESEKALR EAKVFERKLA ENASEIESLN GKIRTSLALI ENYGQRLGEL NEKLKAFAEK ETQSKEKLEA LELTLETARK NEEEAKKAHI ESARLLGEAK KLQANLLRMQ NIKHKISEFE AGIGNLAEKI GFFDREIVER SDRIRQLEGK LEGNRLEELQ QKLARFEEAQ VNITEKIREI TAEKDTLLKE IGMIENSLKR LKELKEELKA LENKRLYLEA VYNNADELEN TYMRVRADMR ARNIGALSIL LNEMFSFMYT NNAYSHIELD PEYNLTVYRK DGTPLEPKLL SGGERAIFNL VLRCAIYRLL ALGFGGDRPD GLPPMILDEP TVFLDRGHVR QLLKLIDMMR SIGVGQIIVV SHDESLIDSA DHVFQVEKDP LTNMSSITKI
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.

Protein Families

SMC family, RAD50 subfamily

Database Links

KEGG: mma:MM_2194

STRING: 192952.MM_2194

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