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Recombinant Methanopyrus kandleri DNA double-strand break repair Rad50 ATPase (rad50), partial

Recombinant Methanopyrus kandleri DNA double-strand break repair Rad50 ATPase (rad50), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

rad50

Purity

>85% (SDS-PAGE)

Target Names

rad50

Uniprot NO.

Q8TXI4

Alternative Names

rad50; sbcC; MK0690; DNA double-strand break repair Rad50 ATPase

Species

Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)

Source

Yeast

Expression Region

1-876

Target Protein Sequence

MIERVKIENL RSHSSTEIEF REGINVLVGP NGAGKTTVLE AITLALFPRT FRSYDHMIRE GERRAVVEVV FWGADGHKYK VRREFYRGGG QRNPRLYREE GDGWKVVASG RAEDVDREVM NALGGVDRDV FREAVYIRQG EIAKLVEATR EERKRIVDRT LGLAEFKKAR EQAHELLRVA EAKLETFRER VRDLKGSKKE LKRVERELEE LKREVKELEP EVEELKERLN ELREAKREFE RLEGELRLLE NKIESLKGRR DDLRKLVEEG KEAERELQRL GDVPSKVREL ENEEAELRRR IEELRNLLDD LRSLRNRLES AEEELEGVKR ELEELKDEAG VDPERLVEFK DKIVEASERL RDLRREEELK RKLEKVSDEL SELGDREETL QSEYEELQER LDEIQGELKE IRVKEKELLE RIESLREAEG ECPVCLRKLP RERAEKLLRD AEKELERLQG REEDLRKERR ELKDRLESVR RELEGTKERM WRLRERREEL ERELEEIEEL KEELADLSRE LGVEEDRLPE LRDLAVRAES LLRDLERRRG DVLRLEKELE RTLDRCEKVI GRTPSGVEDV EEELRRLEEE RDHVGQKLRE AEGELERYHN LEEKVKRARE ARKELKRIER DLEDAKGRLE QVERNLEGLR ERYGSEDRLE EELESVEKKY ERVRDKLSEV KGRLNGMEKR REELKKQVRK YREAKERKER LERVVEVLSL CKEVFRYSRD VAREKVLPAV EREASKILQD LSDRYGSLRI EDDGAVIRVS VPGGHFIEAD RMSGGEKIII GLALRLALAM VGSSFAPFIM LDEPTVHLDA EHRERLAQAL RELDLGKGRV RQAIVVTHDE ELEDAADELW RIENRAGESR VERYSG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.

Protein Families

SMC family, RAD50 subfamily

Database Links

KEGG: mka:MK0690

STRING: 190192.MK0690

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