Recombinant Mesocricetus auratus Transcription factor E2-alpha (TCF3), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
TCF3
Uniprot NO.
Alternative Names
TCF3; PAN; Transcription factor E2-alpha; Immunoglobulin-enhancer-binding factor E12/E47; Transcription factor 3; TCF-3; Transcription regulator Pan
Species
Mesocricetus auratus (Golden hamster)
Source
Yeast
Expression Region
1-649
Target Protein Sequence
MMNQSQRMAP VGSDKELSDL LDFSMMFPLP VANGKGRPAS LAGTQFAGSG LEDRPSSGSW GNSDQNSSSF DPSRTYSEGA HFSESHNSLP SSTFLGPGLG GKSSERSAYA TFGRDTSVSA LTQAGFLPGE LGLSSPGPLS PSGVKSGSQY YPSYPSNPRR RAADSGLDTQ SKKVRKVPPG LPSSVYPSSS GDSYGRDAAA YPSAKTPGSA YPSPFYVADG SLHPSAELWS PPSQAGFGPM LGDGSSPLPL APGSSSVGSG TFGGLQQQER MSYQLHGSEV NGTLPAVSSF SAAPGTYGGA SGHTPPVSGA DSLMGTRGTT ASSSGDALGK ALASIYSPDH SSNNFSPSPS TPVGSPQGLP GTSQWPRAGA PSALSPTYDG GLHGLSKMED RLDEAIHVLR SHAVGTASDL HGLLPGHGAL TTSFPGPVPL GGRHAGLVGG GHPEDGLTSG TSLLHTHASL PSQASSLPDL SQRPPDSYGG LGRAGAPAGA SEIKREEKDD EESTSVADAE EDKKDLKAPR TRTSPDEDED DLLPPEQKAE REKERRVANN ARERLRVRDI NEAFKELGRM CQLHLSSEKP QTKLLILHQA VAVILSLEQQ VRERNLNPKA ACLKRREEEK VSGVVGDPQL ALSAAHPGLG EAHNPPGHL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Transcriptional regulator. Involved in the initiation of neuronal differentiation and mesenchymal to epithelial transition. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Together with TCF15, required for the mesenchymal to epithelial transition. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.
Subcellular Location
Nucleus.
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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