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Recombinant Macaca mulatta POU domain, class 5, transcription factor 1 (POU5F1)

Recombinant Macaca mulatta POU domain, class 5, transcription factor 1 (POU5F1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

POU5F1

Purity

>85% (SDS-PAGE)

Target Names

POU5F1

Uniprot NO.

Q5TM49

Species

Macaca mulatta (Rhesus macaque)

Source

Yeast

Expression Region

1-360

Target Protein Sequence

MAGHLASDFA FSPPPGGGGD GPGGPETGWV DPRTWLSFQG PPGGPGIGPG VGPGSEVWGI PPCPPPYEFC GGMAYCGPQV GVGLVPQGGL ETSQPEGEAG AGVESNSDGA SPEPCTVPTG AVKLEKEKLE QNPEESQDIK ALQKELEQFA KLLKQKRITL GYTQADVGLT LGVLFGKVFS QTTICRFEAL QLSFKNMCKL RPLLQKWVEE ADNNENLQEI CKAETLVQAR KRKRTSIENR VRGSLENLFL QCPKPTLQQI SHIAQQLGLE KDVVRVWFCN RRQKGKRSSS DYAQREDFEA AGSPFSGGPV SFPLAPGPHF GTPGYGSPHF TALYSSVPFP EGEAFPPVPV TTLGSPMHSN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Gene References into Functions

Cytoplasmic CD44 and absence of nuclear Oct3/4 suggest that the cells of cardiac sarcomas may represent 'daughter' stem cells that no longer have the capacity for tumour initiation, but have subsequently developed new lines of partial differentiation. PMID:22804494
Lack of restricted OCT4 protein, and inner cell mass localization of NANOG in primate blastocysts, suggests that NANOG may determine inner cell mass fate more specifically during primate development. PMID:19537945

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

POU transcription factor family, Class-5 subfamily

Database Links

UNIGENE: Mmu.17468

KEGG: mcc:714760

STRING: 9544.ENSMMUP00000020598

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