Abbreviation
Recombinant Cynomolgus monkey CDH1 protein, partial (Active)
Purity
Greater than 95% as determined by SDS-PAGE.
Greater than 95% as determined by SEC-HPLC.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CDH1 at 2 μg/mL can bind Anti-CDH1 recombinant antibody (CSB-RA005034MA2HU). The EC50 is 2.256-2.744 ng/mL.
Alternative Names
Cadherin-1; Epithelial cadherin
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Expression Region
155-708aa
Target Protein Sequence
DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRENIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPVFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYSILSQDPELPDKNMFTINKNTGVISVVTTGLDRESFPMYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPVFNPTTYKGQVPENQANFVITTLKVTDADAPNTPAWEAVYTILNDNDGQFVVTTNPVTNDGILKTAKGLDFEAKQQYILHVAVTNVAPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAREPDTFMEQKITYRIWRDAANWLEINPDTGAISTRAELDREDVEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPESRNLFFCERNPKPQVINIIDADLPPNTSPFTAELMHGASANWTIEYNDPTQESIILKPKIALEVGDYKINLKLMDNQKKDQVTTLEVSVCDCEGAAGICKKAPLVEAGMQIP
Note: The complete
sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is
translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application,
please explicitly request the full and complete sequence of this protein before ordering.
Tag Info
C-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
Storage
Store at -20°C/-81°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Lead Time
3-7 business days
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Shelf Life
The shelf life is related to many factors, storage state, storage temperature and the stability of the product itself. Generally, the shelf life of lyophilized form is 6 months at -20°C/-80°C from the date of receipt.
Datasheet & COA
Please contact us to get it.
Images
-
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
-
Activity
Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CDH1 at 2 μg/ml can bind Anti-CDH1 recombinant antibody (CSB-RA005034MA2HU). The EC50 is 2.256-2.744 ng/mL.
-
The purity of CDH1 was greater than 95% as determined by SEC-HPLC
Description
Cadherin-1 mediates calcium-dependent homophilic cell–cell adhesion in epithelial tissues, and its dysregulation is implicated in tumor invasion and metastasis, making it a critical target for cancer biology studies. This recombinant cynomolgus CDH1 fragment spans residues 155–708, covering the extracellular cadherin repeats essential for adhesive function, and demonstrates specific antibody binding with an EC50 of 2.256–2.744 ng/mL in functional ELISA, confirming proper folding and epitope accessibility. The quantified binding activity supports its use in antibody development and validation workflows, where dose-dependent recognition is required to assess candidate therapeutic or diagnostic reagents. With purity exceeding 95% by SDS-PAGE and endotoxin levels below 1.0 EU/μg, this protein meets the quality thresholds commonly required for cell adhesion assays, migration and invasion studies, and tumor metastasis research involving epithelial-to-mesenchymal transition models.
