Recombinant Influenza C virus RNA-directed RNA polymerase catalytic subunit (PB1), partial

Code
MSDS
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PB1
Uniprot NO.
Species
Influenza C virus (strain C/JJ/1950)
Source
Yeast
Expression Region
1-754
Target Protein Sequence
MEINPYLMFL NNDVTSLIST TYPYTGPPPM SHGSSTKYTL ETIKRTYDYS RTSVEKTSKV FNIPRRKFCN CLEDKDDLVK PTGNVDISSL LGLAEMMEKR MGEGFFKHCV MEAETEILKM HFSRLTEGRQ TYDWTSERNM PAATALQLTV DAIKETEGPF KGTTMLEYCN KMIEMLDWKE VKFRKVKTMV RREKDKRSGK EIKTKVPVMG IDSIKHDEFL IRALTINTMA KDGERGKLQR RAIATPGMIV RPFSKIVETV AQKICEKLKE SGLPVGGNEK KAKLKTTVTS LNARMNSDQF AVNITGDNSK WNECQQPEAY LALLAYITKD SSDLMKDLCS VAPVLFCNKF VKLGQGIRLS NKRKTKEVII KAEKMGKYKN LMREEYKNLF EPLEKYIQKD VCFLPGGMLM GMFNMLSTVL GVSTLCYMDE ELKAKGCFWT GLQSSDDFVL FAVASNWSNI HWTIRRFNAV CKLIGINMSL EKSYGSLPEL FEFTSMFFDG EFVSNLAMEL PAFTTAGVNE GVDFTAAMSI IKTNMINNSL SPSTALMALR ICLQEFRATY RVHPWDSKVK GGRMKIINEF IKTIESKDGL LIADGGKLMN NISTLHIPEE VLKFEKMDEQ YRNRVFNPKN PFTNFDKTID IFRAHGPIRV EENEAVVSTH SFRTRANRTL LNTDMRAMMA EEKRYQMVCD IFKSVFESAD INPPIGAMSI GEAIEEKLLE RAKMKRDIGA IEDSEYEEIK DIIRDAKKAR IESR
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Description

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Target Background

Function
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments. The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching. 5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA. In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs. During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
Subcellular Location
Host nucleus. Host cytoplasm.
Protein Families
Influenza viruses polymerase PB1 family
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