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Recombinant Influenza C virus Non-structural protein 1 (NS)

Recombinant Influenza C virus Non-structural protein 1 (NS)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

NS

Uniprot NO.

Q01639

Alternative Names

NS; Non-structural protein 1; NS1; NS1A

Species

Influenza C virus (strain C/Ann Arbor/1/1950)

Source

Yeast

Expression Region

1-246

Target Protein Sequence

MSDKTVKSTN LMAFVATKML ERQEDLDTCT EMQVEKMKTS TKARLRTESS FAPRTWEDAI KDGELLFNGT ILQTESPTMT PASVEMKGKK FPIDFAPSNI APIGQNPIYL SPCIPNFDGN VWEATMYHHR GATLTKTMNC NCFQRTIWCH PNPSRMRLSY AFVLYCRNTK KICGYLIAKQ VAGIETGIRK CFRCIKSGFV MATDEISLTI LQSIKSGAQL DPYWGNEKPD IDKTEAYMLS LREAGP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Prevents the establishment of the cellular antiviral state initiated by host DDX58, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7. Participates also in the upregulation of the splicing of viral mRNAs.

Gene References into Functions

The introduction of premature translational termination into the NS gene, which blocked the synthesis of the C/NS1 and C/NS2 proteins, drastically reduced the splicing of NS mRNA, raising the possibility that C/NS1 or C/NS2 enhances viral mRNA splicing. PMID:20007279

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Subcellular Location

Host cytoplasm. Host nucleus.

Protein Families

Influenza C viruses NS1 family

Database Links

KEGG: vg:3077236

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