Recombinant Influenza A virus Polymerase acidic protein (PA), partial

Code
MSDS
Size Pls inquire
Source
Conjugate
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Product Details

Purity
Greater than 85% as determined by SDS-PAGE.
Target Names
Name:PA
Uniprot NO.
Alternative Names
PAPolymerase acidic protein; EC 3.1.-.-; RNA-directed RNA polymerase subunit P2
Species
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
Source
E.coli
Expression Region
1-209aa
Target Protein Sequence
MEDFVRQCFNPMIVELAEKAMKEYGEDLKVETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTIVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged and C-terminal Myc-tagged/N-terminal His-SUMO-tagged and C-terminal Myc-tagged/N-terminal His-B2M-tagged and C-terminal Myc-tagged/N-terminal His-GST-tagged and C-terminal Myc-tagged/N-terminal His-tagged/N-terminal His-SUMO-tagged/N-terminal His-B2M-tagged/N-terminal His-GST-tagged/N-terminal GST-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
Subcellular Location
Host cytoplasm. Host nucleus.
Protein Families
Influenza viruses PA family
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