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Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor (vif)

Recombinant Human immunodeficiency virus type 2 subtype A Virion infectivity factor (vif)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

vif

Uniprot NO.

P12452

Species

Human immunodeficiency virus type 2 subtype A (isolate SBLISY) (HIV-2)

Source

Yeast

Expression Region

1-215

Target Protein Sequence

MDQGKRWIAV PTWRVPGRME KWHSLIKYLK YRTKDLEQVR YVPHHKVGWA WWTCSRVIFP LKGNSHLEIQ AYWNLTPEKG WLSSYSVRMT WYSEGFWTDV TPDCADTLIH STYFSCFTAG EVRRAIRGEK SLSCCNYPQA HKSKVPSLQF LALVVVQQND KPQRDNTTRK QWRRNYRRGL RLARQDGRSH KQRGSEPPAQ GAYFPGVAKV LEILA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Counteracts the innate antiviral activity of APOBEC3G. Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions. Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery. Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1. Binds viral RNA and affects the stability of viral nucleoprotein core. May play a role in viral morphology.

Subcellular Location

Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion.

Protein Families

Primate lentivirus group Vif protein family

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