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Recombinant Human herpesvirus 6A Major DNA-binding protein (U41), partial

Recombinant Human herpesvirus 6A Major DNA-binding protein (U41), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

DBP

Uniprot NO.

P52338

Species

Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B lymphotropic virus)

Source

Yeast

Expression Region

1-1132

Target Protein Sequence

MADENETVVS APVSTAAWIY VFPKDKELLD VLSVLSLMER NSPIVISPLL MNLTVENDFS TTVKTPITNF GGTILTKITS FMPVCFFFHG TEQLVGMAED HGDLIRLCEQ TRQKFHLQSF EVPTARKVID IKALCSAVGK DADSVICHVA CGNGFKELLF AGLLIPCVEE QIQVQVGEYS CVKIPLYSAT LFETEETISL SSCTEFIQER GFFLPALSET LFYYVFTSWG TTLRFSNTKE LIDAGLKQFT QDGEQTVKLA PHKTYLGISG QKISAVEKDF LMLVDSVVTE LSFSHVAEYL DSVYDPSQIM NFNDWPIIRN SETHAERMAQ LTNLKLHLSS HLAVLIFAPN SILYCSKLAF IPNVKQAFNS VMTQELLLRS LSFCNALSSL SDDVYNDNRK IIKCDSTSGK DDKFSANHLA YACATSPQLL SFVVWNLNRM SVYNAGNAHT EIYNHLVNCS ANLCEFCDGK CCQSCIGTAM VRVGTRLPAI PKNVKKEPLV MSMFSRYYAE VDILGSFGRK PVSELKEIGK DQQNTLSLDR GKFVSQIFDY CKKNSLIDPV TGEDTFNVRS KKDFVSIIHG LTQCIEECVS RCIVEMRRTQ TPREQIENCL QSFNVDTTPY ATAFSPFLTF SYYKVILTVL QNLALIVASG HVVDRPCTGN SISKWLVQQY QSLYGTFHSS YLKKGFLNTR TVKVASNVDM EQILDCDLYK SGKYVKTTIQ AKLCRLSMQC LRDFRIKNRP FNKSSKTAHN NPYFKKNVKH KKNPLSGCIS FLLFKYHDKL FPNVKISCLE LWQRFLLNNV PKTLDIGNPE EVKTFIKFAF SITNTYDEID IIDIQPECLS TFIDCYFHNK FLSALGFHDY LTSLHGLTSK LVTQNPVLFP VVLDKQPKFS SIQEYLVYVK KLVLDGVPNP VIASLSKEPN FGTIFTSRSL VTFGLTLEKF VSLANREYFQ FGQLGWIGGS GVDRNLNPTS SALQDFRFMR QKTIIATKFS EVIVKKVRRE AIMFDTEVVK GKVLSIVENL TNDIDPELLI IAEVMRDRED KPTMDDMLFF VDGREALAAS IMLKLNHLVD MNVKDFSITN LQSVFETVSS NDAPVYDFSE ILAEEDDQGN GVLKCDETET ETDEPMTKKN RL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Single-stranded DNA-binding protein required for DNA replication.; Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA.

Subcellular Location

Host nucleus.

Protein Families

Herpesviridae major DNA-binding protein family

Database Links

KEGG: vg:1487919

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