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Recombinant Human herpesvirus 2 Envelope glycoprotein B (gB),Partial

Recombinant Human herpesvirus 2 Envelope glycoprotein B (gB),Partial

CSB-EP362479HJX

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Size:

20μg100μg1mg(1mg*1 or 500ug*2)

US$388

Quantity:

Express system: E.coli

Species: Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2)

Tag Info: N-terminal 6xHis-SUMO-tagged

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Product Details
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Target Background

Product Details

Purity

Greater than 90% as determined by SDS-PAGE.

Target Names

Uniprot NO.

P08666

Research Area

others

Species

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2)

Source

E.coli

Expression Region

23-279aa

Target Protein Sequence

APAAPAAPRASGGVAATVAANGGPASRPPPVPSPATTKARKRKTKKPPKRPEATPPPDANATVAAGHATLRAHLREIKVENADAQFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINTKGVCRSTAKYVRNNMETTAFHRDDHETDMELKPAKVATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPY

Mol. Weight

44.4kDa

Protein Length

Partial

Tag Info

N-terminal 6xHis-SUMO-tagged

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Troubleshooting and FAQs

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Datasheet & COA

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Images

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Description

Unlock the potential of virology research with our Recombinant Human herpesvirus 2 Envelope glycoprotein B, an essential protein for understanding the viral fusion process and immune evasion mechanisms in Human herpesvirus 2 (HHV-2) infections. Envelope glycoprotein B, encoded by the gB (UL27) gene, plays a critical role in the Human herpesvirus 2 (strain HG52) life cycle, particularly in viral entry and cell fusion events.

Our Recombinant Human herpesvirus 2 Envelope glycoprotein B is produced in E.coli expression systems, representing a partial length of the protein, covering the 23-279 amino acid expression region. This protein is equipped with an N-terminal 6xHis-SUMO tag, facilitating effective purification and detection processes. With a purity greater than 90% as determined by SDS-PAGE, our recombinant protein ensures reliability and reproducibility in your experiments. The product is available in liquid or lyophilized powder form, providing adaptability for various research applications.

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Target Background

Function

Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.

Subcellular Location

Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein.

Protein Families

Herpesviridae glycoprotein B family

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