Recombinant Human herpesvirus 1 Trans-acting transcriptional protein ICP4 (ICP4), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
ICP4
Uniprot NO.
Alternative Names
ICP4; IE175; RS1; Major viral transcription factor ICP4; Alpha-4 protein; Infected cell protein 4; Transcriptional activator IE175
Species
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Source
Yeast
Expression Region
1-1298
Target Protein Sequence
MASENKQRPG SPGPTDGPPP TPSPDRDERG ALGWGAETEE GGDDPDHDPD HPHDLDDARR DGRAPAAGTD AGEDAGDAVS PRQLALLASM VEEAVRTIPT PDPAASPPRT PAFRADDDDG DEYDDAADAA GDRAPARGRE REAPLRGAYP DPTDRLSPRP PAQPPRRRRH GRWRPSASST SSDSGSSSSS SASSSSSSSD EDEDDDGNDA ADHAREARAV GRGPSSAAPA APGRTPPPPG PPPLSEAAPK PRAAARTPAA SAGRIERRRA RAAVAGRDAT GRFTAGQPRR VELDADATSG AFYARYRDGY VSGEPWPGAG PPPPGRVLYG GLGDSRPGLW GAPEAEEARR RFEASGAPAA VWAPELGDAA QQYALITRLL YTPDAEAMGW LQNPRVVPGD VALDQACFRI SGAARNSSSF ITGSVARAVP HLGYAMAAGR FGWGLAHAAA AVAMSRRYDR AQKGFLLTSL RRAYAPLLAR ENAALTGAAG SPGAGADDEG VAAVAAAAPG ERAVPAGYGA AGILAALGRL SAAPASPAGG DDPDAARHAD ADDDAGRRAQ AGRVAVECLA ACRGILEALA EGFDGDLAAV PGLAGARPAS PPRPEGPAGP ASPPPPHADA PRLRAWLREL RFVRDALVLM RLRGDLRVAG GSEAAVAAVR AVSLVAGALG PALPRDPRLP SSAAAAAADL LFDNQSLRPL LAAAASAPDA ADALAAAAAS AAPREGRKRK SPGPARPPGG GGPRPPKTKK SGADAPGSDA RAPLPAPAPP STPPGPEPAP AQPAAPRAAA AQARPRPVAV SRRPAEGPDP LGGWRRQPPG PSHTAAPAAA ALEAYCSPRA VAELTDHPLF PVPWRPALMF DPRALASIAA RCAGPAPAAQ AACGGGDDDD NPHPHGAAGG RLFGPLRASG PLRRMAAWMR QIPDPEDVRV VVLYSPLPGE DLAGGGASGG PPEWSAERGG LSCLLAALAN RLCGPDTAAW AGNWTGAPDV SALGAQGVLL LSTRDLAFAG AVEFLGLLAS AGDRRLIVVN TVRACDWPAD GPAVSRQHAY LACELLPAVQ CAVRWPAARD LRRTVLASGR VFGPGVFARV EAAHARLYPD APPLRLCRGG NVRYRVRTRF GPDTPVPMSP REYRRAVLPA LDGRAAASGT TDAMAPGAPD FCEEEAHSHA ACARWGLGAP LRPVYVALGR EAVRAGPARW RGPRRDFCAR ALLEPDDDAP PLVLRGDDDG PGALPPAPPG IRWASATGRS GTVLAAAGAV EVLGAEAGLA TPPRREVVDW EGAWDEDDGG AFEGDGVL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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 Customer Reviews

Target Background

Function(From Uniprot)
Plays an essential role in the regulation of viral gene expression by both activating and repressing host RNA polymerase II-mediated transcription. Binds with high affinity to the sequence 5'-ATCGTC-3'. Activates transcription by recruiting a form of the host TFIID to promoters and stabilizing the pre-initiation complex formation. Negatively regulates its own transcription. This immediate early (IE) protein is absolutely necessary for the transition from IE transcription to later viral gene transcription.
Subcellular Location
Host nucleus. Host cytoplasm. Virion tegument.
Protein Families
Herpesviridae ICP4 family
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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