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Recombinant Human cytomegalovirus Protein UL38 (UL38)

Recombinant Human cytomegalovirus Protein UL38 (UL38)

Code
MSDS	MSDS
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

UL38

Uniprot NO.

P16779

Species

Human cytomegalovirus (strain AD169) (HHV-5) (HCMV)

Source

Yeast

Expression Region

1-331

Target Protein Sequence

MTTTTHSTAA IMSLLDEAEW RQTQMDVGGL IQASALGKVA LRYAVRKLMK RGARLRHDSG LYVCICDPSY EFLQMNLSKI SWLERHCPPL DQELIMFGVI EAWEEASVRP TRQLVLFMTP KWDVFAYDSG ILFFLAPSMA QFWHGAIVLE YWNALFPVEV RSHVRQHAHT MDDLVMVFHQ LDYEKQVLEA RRDKNTEGPR TFAKSVNSYV RAILESERRI REGKIPMTFV DRDSLRANSL AHIQATGAQP SHAPAQRVLS APPSLPLPVS EEDPAAAATP SSSAATTPPS SVVPASVESE LSSSPPLPPV VVKDVVYTAG EGDVVQMVVV V

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Description

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Target Background

Function

Plays a role in the inhibition of host apoptosis to facilitate efficient viral replication. Promotes stabilization and inactivation of host TP53 through interaction with host MDM2. Induces host mTORC1 activation by antagonizing the ability of host TSC1/2 to negatively regulate mTORC1. Thus, inhibits a growth regulatory pathway to facilitate viral replication.

Subcellular Location

Host cytoplasm. Host nucleus.

Protein Families

Beta-herpesvirinae UL38 protein family

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