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Recombinant Human cytomegalovirus Major DNA-binding protein (UL57), partial

Recombinant Human cytomegalovirus Major DNA-binding protein (UL57), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

DBP

Uniprot NO.

F5HDQ6

Species

Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)

Source

Yeast

Expression Region

1-1235

Target Protein Sequence

MSHEELTALA PVGPAAFLYF SRLNAETQEI LATLSLCDRS SSVVIAPLLA GLTVEADFGV SVRTPVLCYD GGVLTKVTSF CPFALYFHHT QGIVAFTEDH GDVHRLCEDA RQKYALEAYT PEADRVPTDL AALCAAVGCQ ASETTVHVVV GNGLKEFLFA GQLIPCVEEA TTVRLHGGEA VRVPLYPPTL FNSLQLDAEA DEVSLDARSA FVEARGLYVP AVSETLFYYV YTSWCQSLRF SEPRVLIEAA LRQFVHDSQQ SVKLAPHKRY LGYMSQRLSS LEKDHLMLSD AVVCELAFSF ASVFFDSAYQ PAESMLFSEW PLVTNATDHR DLIRALTELK LHLSTHVAAL VFSANSVLYQ HRLVYLQSSA RHPSAGGTAS QETLLKAIQF TNGLSAACED VYNDARKVLK FQGAPLKDER YGPQHLALVC GTCPQLVSGF VWYLNRVSVY NTGLSGSSTL TNHLVGCAAG LCEACGGTCC HTCYQTAFVR VRTRLPVVPK QPKKEPCVIT VQSRFLNDVD ILGSFGRRYN VDAKDGGLDG KGDDGVPGGG AGGGGGRDVS GGPSDGLGGG RGGGGGGDSG GMMGRGGRML GASVDRTYRL NRILDYCRKM RLIDPVTGED TFSAHGKSDF VAVFSALNKF VDDEALGFVS EVRLKSSRDE VAGATQAFNL DLNPYAVAFQ PLLAYAYFRS VFYVIQNVAL ITATSYIVDN PLTTNLVSKW MTQHFQSIHG AFSTTSSRKG FLFTKQIKSS KNSDHDRLLD FRLYAQGTYA VVPMEIKLSR LSVPTLIMVR VKNRPIYRAG KGNAGSVFFR RDHVPRRNPA KGCLGFLLYR HHERLFPECG LPCLQFWQKV CSNALPKNVP IGDMGEFNAF VKFLVAVTAD YQEHDLLDVA PDCVLSYVES RFHNKFLCYY GFKDYIGSLH GLTTRLTTQN HAQFPHVLGA SPRFSSPAEF ALHVKGLKTA GVPAPMAATV ARESLVRSVF EHRSLVTVPV SVEKYAGINN SKEIYQFGQI GYFSGNGVER SLNVSSMSGQ DYRFMRQRYL LATRLADVLI KRSRRENVLF DADLIKNRVM LALDAENLDC DPEVMAVYEI LSVREEIPAS DDVLFFVDGC EALAASLMDK FAALQEQGVE DFSLENLRRV LDADAQRLTD AAGGEVHDLS ALFAPSGVGA ASGVGGGGLL LGESVAGNSI CFGVPGETGG GCFLVNAGED EAGGVGGSSG GGGGSGLLPA KRSRL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Plays several crucial roles in viral infection. Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation. Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle. Can also catalyze the renaturation of complementary single strands. Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments. This process is driven by the protein which can form double-helical filaments in the absence of DNA.

Subcellular Location

Host nucleus.

Protein Families

Herpesviridae major DNA-binding protein family

Database Links

KEGG: vg:3077528

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