Home
Product
Protein
Recombinant Proteins
Recombinant Human cAMP-dependent protein kinase catalytic subunit gamma (PRKACG)

Recombinant Human cAMP-dependent protein kinase catalytic subunit gamma (PRKACG)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

PRKACG

Uniprot NO.

P22612

Species

Homo sapiens (Human)

Source

Yeast

Expression Region

2-351

Target Protein Sequence

GNAPAKKDT EQEESVNEFL AKARGDFLYR WGNPAQNTAS SDQFERLRTL GMGSFGRVML VRHQETGGHY AMKILNKQKV VKMKQVEHIL NEKRILQAID FPFLVKLQFS FKDNSYLYLV MEYVPGGEMF SRLQRVGRFS EPHACFYAAQ VVLAVQYLHS LDLIHRDLKP ENLLIDQQGY LQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAVGFPPFY ADQPIQIYEK IVSGRVRFPS KLSSDLKHLL RSLLQVDLTK RFGNLRNGVG DIKNHKWFAT TSWIAIYEKK VEAPFIPKYT GPGDASNFDD YEEEELRISI NEKCAKEFSE F
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Phosphorylates a large number of substrates in the cytoplasm and the nucleus.

Gene References into Functions

The missense p.74Ile>Met PRKACG mutation is associated with a marked defect in proplatelet formation and a low level in filamin A in megakaryocytes. PMID:25061177
PKA-mediated phosphorylation of GPIbbeta at Ser(166) negatively regulates VWF binding to GPIb-IX and is one of the mechanisms by which PKA mediates platelet inhibition PMID:12361948
Results suggest that Cgamma and Calpha differ in structure and function in vitro, supporting the hypothesis that functionally different C-subunit isozymes could affect cAMP signal transduction downstream of protein kinase A activation. PMID:15039079

Hide All

Protein Families

Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily

Tissue Specificity

Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.

Database Links

HGNC: 9382

UNIGENE: Hs.158029

KEGG: hsa:5568

STRING: 9606.ENSP00000366488

OMIM: 176893

Promotions