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Recombinant Human Transmembrane protein 109 (TMEM109), partial

Recombinant Human Transmembrane protein 109 (TMEM109), partial

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MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details

Abbreviation

TMEM109

Purity

>85% (SDS-PAGE)

Target Names

TMEM109

Uniprot NO.

Q9BVC6

Alternative Names

TMEM109; Transmembrane protein 109; Mitsugumin-23; Mg23

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro.

Gene References into Functions

MG23 plays a protective role against UVC by accumulating alphaBC in the close vicinity of the ER PMID:23542032
MG23 is an essential component of ER-generated lethal signals provoked upon DNA damage, specifying cell fate under pathophysiological conditions. PMID:20060811

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Subcellular Location

Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.

Database Links

HGNC: 28771

UNIGENE: Hs.13662

KEGG: hsa:79073

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