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Recombinant Human Taste receptor type 2 member 8 (TAS2R8), partial

Recombinant Human Taste receptor type 2 member 8 (TAS2R8), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

TAS2R8

Purity

>85% (SDS-PAGE)

Target Names

TAS2R8

Uniprot NO.

Q9NYW2

Species

Homo sapiens (Human)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

Gene References into Functions

targets cancer stem cells by suppressing cancer stemness characteristics and neuroblastoma cell invasion PMID:28467517
Human bitter taste receptors hTAS2R8 and hTAS2R39 display differential functions to recognize bitter peptides. PMID:21670512

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Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor T2R family

Tissue Specificity

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

Database Links

HGNC: 14915

UNIGENE: Hs.533755

KEGG: hsa:50836

STRING: 9606.ENSP00000240615